不发酵糖菌所致医院获得性肺炎危险因素探讨  

Risk factors analysis in hospital-acquired pneumonia caused by nonfermentative bacteria

作　　者：魏宏建[1] 刘丽丽[1] 肖李乐云[1] 董丽宏[1] 任婵[1] 顾姗姗[1] 

机构地区：[1]昆明医学院第一附属医院ICU,650031

出　　处：《中国感染与化疗杂志》2007年第5期356-358,共3页Chinese Journal of Infection and Chemotherapy

摘　　要：目的探讨ICU不发酵糖菌所致医院获得性肺炎的危险因素。方法采用非条件Logistic回归法,回顾性研究近5年我院ICU医院获得性不发酵糖菌肺炎的相关危险因素。结果单因素分析发现年龄、糖尿病、恶性肿瘤、慢性阻塞性肺疾病(COPD)、吸烟史、格拉斯哥昏迷评分(GCS)、急性生理功能和慢性健康状况评分系统Ⅱ(APACHEⅡ)评分等22个相关危险因素。多因素分析结果,COPD、胃酸分泌抑制剂、镇静剂、误吸、机械通气和气管插管/切开6个为高危因素。结论患者误吸、COPD、胃酸分泌抑制剂、使用镇静剂、机械通气、气管插管/切开是导致医院获得性不发酵糖菌肺炎的危险因素;而患者昏迷、胸腹部手术、低血清白蛋白血症和糖尿病等基础疾病也是值得关注的问题。Objective To analyze the risk factors of hospital acquired pneumonia （HAP） caused by nonfermentative bacteria in ICU. Methods Using binary logistic regression analysis, we reviewed the related risk factors of hospital acquired pneumonia caused by nonfermentative bacteria from January, 2002 to May, 2006 in ICU of our hospital. Results Univariate regression analysis identified 22 variables associated with HAP, including age, diabetes mellitus, malignant tumor, chronic obstructive pulmonary disease （COPD）, smoking, Glasgow Coma Scale （GCS） score, Acute Physiology and Chronic Healthy EvaluationⅡ （APACHEⅡ） score. Multivariate regression analysis confirmed 6 high risk factors： aspiration, COPD, use of antacids, sedative agents, mechanical ventilation and tracheal intubation or tracheostomy. Conclusions Aspiration, COPD, use of antacids, sedative agents, mechanical ventilation, tracheal intubation or tracheostomy are high risk factors associated with HAP.

关 键 词：不发酵糖菌 医院获得性肺炎 危险因素 

分 类 号：R563.1[医药卫生—呼吸系统]