肾康注射液治疗慢性肾衰临床疗效观察  

Observation of Curative Efficacy of Shenkang Injection for Chronic Renal Failure

作　　者：龚云[1] 朱春玲[1] 谭猛[1] 

机构地区：[1]贵阳医学院附属医院肾内科,贵阳市550001

出　　处：《中国药房》2007年第30期2376-2377,共2页China Pharmacy

摘　　要：目的:观察新型中药复方制剂肾康注射液治疗慢性肾功能衰竭(CRF)的临床疗效。方法:将84例CRF患者随机分为2组。在常规降压治疗基础上,治疗组(54例)给予肾康注射液60～100mL,溶于10%葡萄糖注射液300mL或生理盐水300mL中静脉滴注,1次.d-1,30d为一个疗程;对照组(30例)给予复方丹参注射液250mL静脉滴注,1次.d-1,30d为一个疗程。结果:与对照组比较,治疗组的血清肌酐、尿素氮下降更显著(P<0.05);内生肌酐清除率上升亦更显著(P<0.05)。结论:肾康注射液对CRF的临床治疗具有重要意义,且疗效优于复方丹参注射液。OBJECTIVE： To observe the clinical efficacy of Shenkang injection, a new compound preparation for chronic renal failure （CRF） . METHODS： A total of 84 CRF patients were randomly divided into two groups： the treatment group （n = 54） was given routine antihypertensive therapy and infused （iv gtt） with Shenkang injection 60-100mL （dissolved in 10%GS 300mL or NS 300mL） q.d for 30d; the control group（n =30） was infused （iv gtt） with Compound danshen injection 250mL q.d for 30d. RESULTS： As compared with the control group, serum levels of creatinine and urea nitrogen（UN） in treatment group had a greater reduction （P〈 0.05）, and the endogenous creatinine clearance rate had a greater increase than in control group（P〈 0.05） . CONCLUSION： Shenkang injection is of great clinical importance for CRF, and its efficacy is superior to that of Compound danshen injection.

关 键 词：慢性肾功能衰竭 肾康注射液 临床疗效 复方丹参注射液 

分 类 号：R283.61[医药卫生—中药学] R983[医药卫生—中医学]