Spectrometric study of α-methylene aromatic araminenone and aminoketone  

作　　者：Li Yuan Mou Zi Yun Lin Li Ya Zhu Xiao Tian Liang 

机构地区：[1]Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China [2]Center for Biophysical Science and Engineering, University of Alabama at Birmingham, Birmingham, AL 35294, USA

出　　处：《Chinese Chemical Letters》2007年第10期1253-1255,共3页中国化学快报（英文版）

基　　金：supported by the National Natural Science Foundation of China(No.39970867).

摘　　要：Thirteen α-methylene aromatic araminenone and four α-methylene aromatic aminoketones were prepared by modified Mannich reaction. On the basis of isotopic labeling, a plausible way of cleavage was proposed for the formation of the M^＋- 17 fragment peak in the MS of the α-methylene aromatic araminenone and aminoketones. The characteristic chemical shift of the olefinic protons in ^1H NMR is also discussed.Thirteen α-methylene aromatic araminenone and four α-methylene aromatic aminoketones were prepared by modified Mannich reaction. On the basis of isotopic labeling, a plausible way of cleavage was proposed for the formation of the M^＋- 17 fragment peak in the MS of the α-methylene aromatic araminenone and aminoketones. The characteristic chemical shift of the olefinic protons in ^1H NMR is also discussed.

关 键 词：α-Methylene aromatic araminenone and aminoketones Spectrometric study 

分 类 号：O6[理学—化学]