The complexes of multiimidazole with copper(Ⅰ) display tyrosinase activity  

作　　者：Rong Xiao Xiao Yu Su Ru Gang Xie 

机构地区：[1]College of Chemistry, Sichuan University, Chengdu 610064, China

出　　处：《Chinese Chemical Letters》2007年第10期1278-1280,共3页中国化学快报（英文版）

基　　金：the support from the National Natural Science Foundation of China(No.20172038).

摘　　要：The six multiimidazole copper（Ⅰ） complexes are utilized to mimic tyrosinase. The main product is 3,5-di-t-butylcatechol from o-hydroxylation of the substrate 2,4-di-t-butylphenol. The highest yield of catechol is up to 82.2% and selectivity 94.8% by [Cu（Ⅰ）2（3b）（MeCN）2]（CIO4）2 and O2 under mild conditions, which are found to be more efficient than that already reported.The six multiimidazole copper（Ⅰ） complexes are utilized to mimic tyrosinase. The main product is 3,5-di-t-butylcatechol from o-hydroxylation of the substrate 2,4-di-t-butylphenol. The highest yield of catechol is up to 82.2% and selectivity 94.8% by [Cu（Ⅰ）2（3b）（MeCN）2]（CIO4）2 and O2 under mild conditions, which are found to be more efficient than that already reported.

关 键 词：Multiimidazole dicopper（Ⅰ） complex o-Hydroxylation CATECHOL Tyrosinase model 

分 类 号：O62[理学—有机化学]