新型灭螺剂氯代水杨胺灭螺效果研究  

Molluscicidal effect of a novel molluscicide,LDS

作　　者：徐兴建[1] 元艺[1] 李桂玲[2] 魏凤华[1] 赵云斌[2] 涂祖武[1] 刘敏[2] 曹慕民[1] 何汇[1] 范宏萍[1] 

机构地区：[1]湖北省疾病预防控制中心血吸虫病防治研究所,武汉430079 [2]华中科技大学同济医学院

出　　处：《中国血吸虫病防治杂志》2007年第5期328-333,共6页Chinese Journal of Schistosomiasis Control

基　　金：国家高技术研究发展计划(863计划)(2004AA2Z3560)

摘　　要：目的观察新型灭螺剂氯代水杨胺(LDS)的灭螺效果。方法采用浸杀法、喷洒法和撒粉法,将10%LDS和50%氯硝柳胺乙醇胺盐(WPN)在实验室分别配成0.05、0.1、0.2、0.4、0.8、1.6、3.2mg/L(g/m2)7个浓度,在现场分别配成0.2、0.4、0.8mg/L(g/m2)3个浓度,平行比较两种药物实验室24、48、72h和现场1、3、7d的灭螺效果。两种药物均以0.4mg/L(g/m2)浓度评价其灭螺效果。结果在实验室温度23～25℃条件下,LDS和WPN的钉螺死亡率,浸杀72h分别为100.0%和96.7%;喷洒7d分别为100.0%和96.0%;撒粉7d分别为92.0%和94.0%。在现场温度15～24℃条件下,LDS和WPN的钉螺死亡率,浸杀72h分别为100.0%和96.0%;喷洒7d分别为100.0%和96.9%;撒粉7d分别为100.0%和94.1%。结论新型灭螺剂氯代水杨胺的灭螺效果与氯硝柳胺乙醇胺盐基本相同,但灭螺费用降低。Objective To evaluate the molluscicidal effect of a novel molluscicide of quinoid 2＇ , 5-dichloro-4＇-nitrosalicylanilide, LDS. Methods The parallel experiment with LDS and niclosamide,WPN was carried out by means of immersion, insufflations and powdering in lab and the field and there were seven concentrations of 0.05, 0.1, 0.2, 0.4, 0.8, 1.6, 3.2 mg/L（g/m^2） in lab and three dosages of 0.2, 0.4, 0.8 mg/L（g/m^2） in the field. The molluscicidal effects of 24, 48, 72 h and 1, 3, 7 d mortality of the Oncornelania snails were investigated with the dosage of 0.4 mg/L（g/m^2） for both of the molluscicides. Results Under the room temperature of 23 25 ℃, for exposure 72 h by the immersion method, the snail death rates of LDS and WPN were 100.0% and 96.7%, respectively; for exposure 7 d by the insufflations method, the snail death rates were 100.0% and 96.0%, respectively; for exposure 7 d by the powdering method, the snail death rates were 92.0% and 94.0%, respectively in lab. Under the field temperature of 15-24 ℃, for exposure 72 h by the immersion method, the snail death rates of LDS and WPN were 100.0% and 96.0%, respectively; for exposure 7 d by the insufflations method, the snail death rates were 100.0% and 96.9%, respectively; for exposure 7 d by powdering method, the snail death rates were 100.0% and 94.1%, respectively in the field. Conclusions The parallel experiment of LDS and WPN by the three methods shows that their molluscicidal effects are basically the same in lab and the field. However, the cost of LDS is less than that of WPN.

关 键 词：灭螺剂 氯代水杨胺 灭螺效果 钉螺 

分 类 号：R383.24[医药卫生—医学寄生虫学]