41例药品不良反应报告分析  

Analysis of 41 adverse drug reactions

作　　者：杨彤[1] 任洁雯[1] 黎颖怡[1] 

机构地区：[1]广州市儿童医院,广东广州510120

出　　处：《儿科药学杂志》2007年第5期30-31,共2页Journal of Pediatric Pharmacy

摘　　要：目的:了解我院药品不良反应(ADR)发生的特点和规律,为临床合理用药提供信息。方法:对我院2005年5月～2006年4月上报的41例ADR分别从报告人、引起ADR的药品种类、给药途径、临床表现等方面进行统计分析。结果:ADR报告者主要是医生(78.05%)和护士(19.51%)。在41例ADR中涉及抗生素17例占41.46%,中药注射剂12例占29.27%。经静脉给药引起的ADR 33例占80.49%。ADR表现以皮肤及附件损伤为主。结论:临床在使用抗生素及中药注射剂时,特别是静脉给药时,要严密监测,有不良反应征兆时及时处理,以免发生更严重的ADR。Objective： To investigate the characteristics and the regalar patterns of adverse drug reaction （ADR） in our hospital and provide necessary information for reasonable clinical administration of medicines. Methods： 41 ADR cases reported in our hospital from May 2005 to April 2006 were analyzed in terms of reporters, drug categories, routes of administration, clinical manifestation, etc. Results： Most ADR cases were reported by physicians （78.05 % ） and nurses （ 19.51% ）. In 41 ADR cases, 17 cases related to antibiotics accounted for 41.46 % ; 12 cases related to traditional Chinese medicine injections accounted for 29.27%. In all 41 ADR cases, 33 cases （80.49%） were applied intravenously. The most common symptom of ADR were the lesion of skin and appendants. Conclusions： More attention should be paid to antibiotics and traditional Chinese medicine injections, especially by intravenous injection. When signs of ADR emerged, a prompt treatment should be carried out to avoid severe ADR.

关 键 词：药品不良反应 抗生素 中药注射剂 静脉给药 

分 类 号：R961[医药卫生—药理学]