可控制性卵巢刺激治疗中促性腺激素释放激素激动剂降调节与卵巢过度抑制  

Ovarian poor responder correlated with GnRH-a down regulation

作　　者：李洁[1] 谭真[1] 任姿[1] 庄广伦[1] 

机构地区：[1]中山大学附属第一医院生殖医学中心,广州510080

出　　处：《生殖医学杂志》2007年第5期306-308,共3页Journal of Reproductive Medicine

摘　　要：The retrospective study showed that 87.4%(248/279) ovarian poor responder could be reversed by reduced the dose of GnRH-a or increased initial Gn dose compared with full or a half dose and one third dose of GnRH-a down-regulation groups,only 11.1%(31/279) cases taken place ovarian poor responder again in next IVF-ET cycle.The result implied that profound ovarian suppression could be reversed by reduced GnRH-a dose or increased Gn dose in women with ovarian normal function.The dose of GnRH-a may have an impact on the steroidgenesis in IVF-ET cycles.The retrospective study showed that 87.4% （248/279） ovarian poor responder could be reversed by reduced the dose of GnRH-a or increased initial Gn dose compared with full or a half dose and one third dose of GnRH-a down-regulation groups, only 11.1% （31/279） cases taken place ovarian poor responder again in next IVF-ET cycle. The result implied that profound ovarian suppression could be reversed by reduced GnRH-a dose or increased Gn dose in women with ovarian normal function. The dose of GnRH-a may have an impact on the steroidgenesis in IVF-ET cycles.

关 键 词：促性腺激素释放激素激动剂 卵巢低反应 类固醇生成 

分 类 号：R711.5[医药卫生—妇产科学]