麻黄多糖对绵羊红细胞所致小鼠溶血素生成的影响  

Effect of ephedran on erythrocytolysin formation of mouse caused by sheep erythrocyte

作　　者：孟达理[1] 严士海[2] 许芝银[1] 

机构地区：[1]江苏省中医院外科,江苏南京210029 [2]江苏省中医院科技处,江苏南京210029

出　　处：《江苏大学学报（医学版）》2007年第5期379-380,385,共3页Journal of Jiangsu University：Medicine Edition

摘　　要：目的:观察麻黄多糖对绵羊红细胞所致小鼠溶血素生成的影响(比色法),以了解麻黄多糖对正常小鼠免疫功能的作用。方法:运用免疫实验方法检测了正常小鼠空白组和实验组在脾指数、胸腺指数和溶血素水平等方面的测定。结果:麻黄多糖大剂量(132 mg/kg)组小鼠胸腺指数下降,与空白组相比差异有统计学意义(P<0.05)。麻黄多糖3个剂量组均能使正常小鼠的半数溶血值(HC50)下降,与空白组比较,差异有统计学意义(P<0.01)。结论:麻黄多糖对正常小鼠体液免疫具有一定的抑制作用。Objective： To observe the influence of ephedran on erythrocytolysin antibody formation of mouse caused by sheep erythrocyte and explore the effect of ephedran on the immune function of the mouse. Methods： To detect the spleen index, the thoracic gland index, and erythrocytolysin of the mouse. Resuits ： The 132 mg/kg group of ephedran can significantly lower the thoracic gland index of the mouse （P 〈 0.05 ）. The 33 mg/kg, 66 mg/kg, 132 mg/kg groups of ephedran can all remarkably descend the erythrocytolysin level （P 〈 0.01 ）. Conclusion： The ephedran had some depressant effect on the humoral immunity of the mouse.

关 键 词：麻黄多糖 溶血素 体液免疫 

分 类 号：R966[医药卫生—药理学]