肺心病慢性呼吸衰竭患者脑诱发电位的研究  

A study on evoked potentials in cor pulmonale patients with chronic respiratory failure

作　　者：乔慧[1,2] 蔡凤云[1,2] 刘淑玲 谭郁玲[1,2] 

机构地区：[1]北京市神经外科研究所 [2]北京天坛医院呼吸内科

出　　处：《中华老年医学杂志》1997年第1期43-45,共3页Chinese Journal of Geriatrics

摘　　要：目的用诱发电位方法检测肺心病慢性呼吸衰竭患者在发生临床肺性脑病前脑功能的改变。方法对２８例老年肺心病慢性呼吸衰竭无肺性脑病临床表现的患者、２０例老年肺炎患者及３０例老年健康人同时进行脑干听觉、体感诱发电位（ＢＡＥＰ、ＳＥＰ）检查。结果ＢＡＥＰ异常：肺心病组２３例（８２％），肺炎组７例（３５％）；ＳＥＰ异常：肺心病组２４例（８６％），肺炎组８例（４０％）。经统计学检验，肺心病组ＢＡＥＰ、ＳＥＰ与健康组、肺炎组差异有显著性，肺炎组与健康组差异无显著性。结论肺心病慢性呼吸衰竭患者有脑干功能受损和弥漫性脑功能障碍。Objective Evoked potential was used to detect the change of brain function in cor pulmonale patients with chronic respiratory failure before the appearence of clinical symptoms of pulmonary encephalopathy. Methods All recruits including 28 cor pulmonale patients, 20 pneumonia patients and 30 healthy control subjects of same age range were studied simultaneously with brain stem auditory evoked potential (BAEP) and somatosensory evoked potential (SEP). Results The abnormal ratios of BAEP and SEP for the cor pulmonale patients were 23(82%) and 24(86%) respectively, while those for the pneumonia patients were 7(35%) and 8(40%). With statistical test, there was an obvious difference ( P <0 01) for cor pulmonale patients but not for the pneumonia patients. Conclusions The cor pulmonale patients with chronic respiratory failure might have brain stem damage and brain function impairment.

关 键 词：呼吸功能不全 肺心病 诱发电位 

分 类 号：R541.502[医药卫生—心血管疾病]