脉冲辐解法研究Cu(Ser)_2和Cu(Gly─Gly)_2催化哦O_2^(. -)歧化反应的动力学  

KINETICS STUDY ON DISMUTATION OF SUPEROXIDE ION CATALYZED BY Cu(Ser)_2 AND Cu(Gly-Gly)_2 BY USING PULSE RADIOLYSIS

作　　者：谢英[1] 邓希贤[1] 金虬[1] 李大珍[1] 李凤梅[2] 

机构地区：[1]北京师范大学化学系,北京100875 [2]北京师范大学低能核物理研究所,北京100875

出　　处：《北京师范大学学报（自然科学版）》1997年第2期226-230,共5页Journal of Beijing Normal University(Natural Science)

基　　金：国家自然科学基金!29373092

摘　　要：以自行合成的丝氨酸铜Cu（Ser）2和甘氨酰甘氨酸铜Cu（Gly-Gly）2作为SOD模拟物，在pH7．8及（20．0±0．5）℃条件下，用脉冲辐解法分别研究其催化超氧阴离子自由基（O）歧化反应的动力学，得到了反应级数n及催化速率常数kcat，并初步探讨了反应机理．证实了水溶液中Cu（Ⅱ）－氨基酸络合物催化O歧化反应乒乓机理中的第一步反应是整个反应过程的速控步骤．Cu(Ser)2 and Cu(Gly-Gly)2, as analogues of SOD were prepared. Kinetics of dismutation of superoxide ion catalyzed by Cu(Ser)2 and Cu(Gly-Gly)2 by using pulse radiolysis were studied at PH 7.8 and (20.0±0.5)℃. The rate constants Kcat, the reaction order n were obtained and the catalyst mechanism was probed. The first step in the mechanism is the determined step was proved.

关 键 词：超氧阴离子 自由基 催化 SOD 丝氨酮铜 歧化反应 

分 类 号：O629.8[理学—有机化学] Q554[理学—化学]