丹芍行气活血汤对慢性盆腔炎患者热休克蛋白60抗体的影响  

Tang on C - HSP60 in CPID

作　　者：冯筠 宁艳 彭小鹏 马宪丽 Feng Jun, Ning Yan, Peng Xiaopeng, Ma Xianli

机构地区：深圳市中医院,广东深圳518040

出　　处：《中国保健》2007年第14期11-13,共3页Chinese Health Care

摘　　要：目的：观察丹芍行气活血汤对抗热休克蛋白60（HSP60）抗体阳性的慢性盆腔炎的临床疗效。方法：将274例患者随机分为丹芍行气活血汤组、阿奇霉素组和丹芍行气活血汤加阿奇霉素组。观察治疗前后患者症状、体征、血清HSP60抗体IgG、宫颈黏液CT的变化。结果：三组临床综合疗效分别为84.44%、81.11%和85.11%,比较无显著性差异;三组治疗前后血清HSP60IgG浓度比较均有显著性差异（P〈0.05）,而组间比较无显著性差异。三组治疗后宫颈分泌物CT转阴率比较,丹芍行气活血汤加阿奇霉素组为100%,丹芍行气活血汤组为63.58%,阿奇霉素组为64.12%,丹芍行气活血汤加阿奇霉素组与其余两组结果有显著性差异（P〈0.05）,其余两组之间比较无差异性。结论：三组均可改善和消除慢性盆腔炎患者的临床症状和体征,在治疗下生殖道CT感染中,丹芍行气活血汤加阿奇霉素联合治疗较单纯中药及单纯西药治疗更为有效。Objective：To observe the effects of Danshaoxingqihuoxue Tang on CPID with positive C - HSP60. Methods：two hundred and seventy- four patients were divided into 3 groups on randome：l st group （treated with Danshaoxingqihuoxue Tang） ,2nd group （treated with Azithromycin） ,3rd group（ treated with Danshaoxingqihuoxue Tang and Azithromycin）. Then observed the changes of every patient＇s symptoms, signs, serum C - HSP60 antibody IG,and cervical mucus CT. Results：the total effective rate of these 3 groups had no significant difference. Every patient＇ s IG concentration in 3 groups decreased after treatment, with significant difference （P 〈 0. 05 ）, but there was no obvious difference among 3 groups. The rate of cervical mucus CT positive to negative is 100% in 3rd group,63.58% in 1st group,and 64. 12% in 2nd group;there were significant differences between 3rd group and other two groups（ P 〈 0. 05 ）, but no significant difference between 1 st group and 2nd group. Conclusion： the symptoms and signs of CPID can be relieved after treatment in each group. The combined therapy is more effective in the treatment of infra - genital tract CT infection than therapies by only Chinese or western drugs.

关 键 词：慢性盆腔炎 C-HSP60抗体 丹芍行气活血汤 阿奇霉素 

分 类 号：R711.33[医药卫生—妇产科学;医药卫生—临床医学]