国产硝酸异山梨酯注射液治疗冠心病心绞痛  

DOMESTIC ISOSORBIDE DINITRATE INJECTION IN TREATMENT OF 41 CASES OF ANGINA PECTORIS

作　　者：徐济民[1,2] 黄震华[1,2] 郑慧君[1,2] 盛净[1,2] 王健[1,2] 朱亮[1,2] 陆琛[1,2] 

机构地区：[1]上海第二医科大学附属第九人民医院心内科 [2]上海第一生化药业公司

出　　处：《中国新药杂志》1997年第1期46-49,共4页Chinese Journal of New Drugs

摘　　要：应用国产硝酸异山梨酯（２０ｍｇ加入５％葡萄糖液５００ｍｌ中，２．４ｍｇ／ｈ静脉滴注，ｑｄ，连用１４ｄ）治疗冠心病心绞痛病人４１例。临床总有效率为９２．７％，心电图总有效率为６８．３％，与进口硝酸异山梨酯总有效率分别为９０％及６５％基本相近。该药尚有扩张血管、降低血压、减少心肌氧耗、改善左室功能等作用。Domestic isosorbide dinitrate injections were adopted to treat 41 cases of angina pectoris in a daily dose of 20 mg for 14 d and a total effective rate of 92.7% and a ECG effective rate of 68.3% were obtained,which were comparable to that obtained by imported drug Isoket.

关 键 词：硝酸异山梨酯 心绞痛 注射液 冠心病 

分 类 号：R541.405[医药卫生—心血管疾病]