零包海洛因的成分、含量以及海洛因滥用者尿液中吗啡/可待因比值  

COMPONENT AND PURITY OF RETAIL HEROIN AND THE CONCENTRATION RATIOS OF MORPHINE TO CODEINE IN URINE OF HEROIN ABUSERS

作　　者：刘美丽[1] 宋朝锦[2] 乔静[2] 王玉瑾[1] 

机构地区：[1]山西医科大学法医学院,太原030001 [2]北京市公安局法医鉴定中心,北京100085

出　　处：《中国药物依赖性杂志》2007年第5期386-389,共4页Chinese Journal of Drug Dependence

基　　金：山西省自然科学基金资助项目(20011066);山西高校科技研究开发项目(20041319)

摘　　要：目的:探讨零包海洛因的成分、含量及海洛因滥用者尿液中吗啡/可待因比值。方法:采用气相色谱/质谱联用法(GC/MS)和气相色谱法(GC)检测105份海洛因滥用者的尿样及441件零包海洛因,并作描述性统计分析。结果:105份尿样中有9份检出海洛因原体(其中三份同时检出O6-单乙酰吗啡);30份仅检出吗啡和可待因,其中吗啡/可待因峰面积比值小于1的有13份。441件零包中海洛因含量的最大值是95.2%,最小值为0;乙酰可待因含量的最大值是89.3%,最小值是1.6%。乙酰可待因含量比海洛因含量大的零包有25例,占到5.7%。结论:零包中海洛因中的成分及含量差别大;嫌疑人的尿液中吗啡/可待因浓度比小于1时,不能排除有吸食海洛因的可能。Objective： To analyze the component and purity of retail heroin and determine the concentration ratios of morphine to codeine in the urine of herion abusers. Methods：Four hundred and forty one pieces of retai heroin and 105 urine samples were determined by gas chromatography - mass spectrometry （GC/MS） and gas chromatography （GC）, and the result was statistically analyzed. Results： In 105 urine samples, 9 pieces contained heroin （ including three pieces with 6 - monoacetylmorphine simultaneously）; 30 samples only had morphine and codeine, and among them, there were 13 samples whose morphine/codeine ratio was lower than 1. The composition of the 441 pieces of retail heroin varied from 95.2% to 0% ; The composition of acetyl codeine varied from 89.3% to 1.6% ; 25 pieces （accounting for 5.7% ） contained more acetyl codeine than heroin. Conclusion： The composition and quantity of retail heroin are quite different. With acetyl codeine more than heroin in one piece of heroin, the concentration ratios of morphine to codeine in urine may be lower than 1. But it dose not mean the sample＇ s owner has not used heroin.

关 键 词：海洛因 吗啡 可待因 尿液 影响 

分 类 号：R595.5[医药卫生—内科学]