高效液相色谱法测定藏茵陈注射液中獐芽菜苦苷的含量  

Determination of Swertiamarin Content in Zangyinchen Injection by HPLC

作　　者：贾珍[1] 杨凤梅[2] 

机构地区：[1]青海省人民医院,西宁810007 [2]青海省药品检验所,西宁810001

出　　处：《中国现代应用药学》2007年第5期392-393,共2页Chinese Journal of Modern Applied Pharmacy

摘　　要：目的建立藏茵陈注射液中獐芽菜苦苷的含量测定方法。方法HPLC测定藏茵陈注射液中獐芽菜苦苷的含量。采用C18色谱柱,以甲醇-水(20∶80)为流动相,检测波长254 nm。结果此方法线性关系良好(r=0.999 5),平均回收率为98.9%,RSD=0.39%(n=9)。结论本方法简便,稳定,能有效地控制该制剂的质量。　OBJECTIVE To establish HPLC determination method of swertiamarin in Zangyinchen Injection.METHODS The HPLC method was carried out with C18 column.Methanol∶water（20∶80） was used as a mobile phase.The UV detection wavelength was 254 nm. RESULTS The linearity of this method was good（r=0.999 5） and Average recovery was 98.9% with RSD=0.39%（n=9）.CONCLUSION The method is simple,rapid and reliable for quality control of the Zangyinchen injection.

关 键 词：獐芽菜苦苷 藏茵陈注射液 高效液相色谱法 

分 类 号：R917.101[医药卫生—药物分析学] R931.6[医药卫生—药学]