NUMERICAL SIMULATION BY COMPUTATIONAL FLUID DYNAMICS AND EXPERIMENTAL STUDY ON STIRRED BIOREACTOR WITH PUNCHED IMPELLER  

作　　者：WANG Yu HE Pingting YE Hong XIN Zhihong 

机构地区：[1]College of Food Science and Technology, Nanjing Agricultural University, Nanjing 210095, China [2]College of Material Science and Technology, Nanjing University of Aeronautics and Astronautics Nanjing 210016, China

出　　处：《Chinese Journal of Mechanical Engineering》2007年第5期42-45,共4页中国机械工程学报（英文版）

基　　金：This project is supported by Provincial Science Technology Committee of Jiangsu China(No.BJ99025).

摘　　要：Instantaneous flow field and temperature field of the two-phase fluid are measured by particle image velocimetry （PIV） and steady state method during the state of onflow. A turbulent two-phase fluid model of stirred bioreactor with punched impeller is established by the computational fluid dynamics （CFD）, using a rotating coordinate system and sliding mesh to describe the relative motion between impeller and baffles. The simulation and experiment results of flow and temperature field prove their warps are less than 10% and the mathematic model can well simulate the fields, which will also provide the study on optimized-design and scale-up of bioreactors with reference value.Instantaneous flow field and temperature field of the two-phase fluid are measured by particle image velocimetry （PIV） and steady state method during the state of onflow. A turbulent two-phase fluid model of stirred bioreactor with punched impeller is established by the computational fluid dynamics （CFD）, using a rotating coordinate system and sliding mesh to describe the relative motion between impeller and baffles. The simulation and experiment results of flow and temperature field prove their warps are less than 10% and the mathematic model can well simulate the fields, which will also provide the study on optimized-design and scale-up of bioreactors with reference value.

关 键 词：Stirred bioreactor with punched impeller Computational fluid dynamics（CFD）Particle image velocimetry（PIV） Flow field Temperature field 

分 类 号：TH79[机械工程—仪器科学与技术]