感冒止咳颗粒质量标准研究  

Study on the quality standard of Ganmaozhike granule

作　　者：沈志轩 邹义栩[2] 张怡评[3] 林丽聪[3] 

机构地区：[1]漳州市药品检验所,漳州363000 [2]福建省药品检验所,福州350001 [3]福建中医学院,福州350003

出　　处：《海峡药学》2007年第10期42-44,共3页Strait Pharmaceutical Journal

摘　　要：目的建立感冒止咳颗粒质量标准。方法采用TLC法对制剂中黄芩、金银花、葛根、连翘进行薄层色谱鉴别；采用HPLC法测定制剂中黄芩苷的含量。结果TLC可检出黄芩、金银花、葛根、连翘；黄芩苷含量在1．49μg·mL^-1～149．00μg·mL^-1范围内线性良好，Y=3372．4X-2．8342（r=1．0000），平均回收率为101．3％，RSD为0．68％。结论本法简便、准确、可靠、重复性好，可用于感冒止咳颗粒的质量控制和评价。OBJECTIVE To establish a quality standard of Ganmaozhike granule. METHODS Radix Scutellariae, Flos Lonicerae, Radix Puerariae, Fructus Forsythiae were identified by TLC. Baicalin was determined by HPLC. RESULTS Radix Scutellariae, Flos Lonicerae, Radix Pueratiae, Fructus Forsythiae could be identified by TLC. The standard curve was linear within the range of 1.49 - 149.0μg, Y = 3372.4X -2. 8342 （r = 1. 000）, the average recovery was 101.3% ,RSD =0.685（n =9）. CONCLUSION The method is simple,rapid,accurate,reproducible and can be used to control the quality of Ganmaozhike granule.

关 键 词：感冒止咳颗粒 质量标准 黄芩苷 

分 类 号：R927.11[医药卫生—药学]