Chemical constituents from Xylosma controversum  

南岭柞木化学成分(英文)

作　　者：徐正仁[1] 陆亚男[1] 柴兴云[1] 任宏燕[1] 屠鹏飞[1] 

机构地区：[1]北京大学药学院天然药物学系,北京100083

出　　处：《Journal of Chinese Pharmaceutical Sciences》2007年第3期218-222,共5页中国药学（英文版）

基　　金：Program for Changjiang Scholar and InnovativeTeam in Peking University (Grant number: 985-2-063-112).

摘　　要：Aim To study the chemical constituents from the stems of Xylosma controversum Clos. Methods The constituents were isolated by solvent extraction, repeated chromatography with silica gel, Sephadex LH-20, and RP-18 columns. The structures were elucidated by spectral analysis. Results Thirteen compounds were isolated and their structures were identified as （-）-syringaresinol （1）, syringaresinol-4-O-β-D-glucopyranoside （2）, syringaresinol-4,4′-bis-O-β-D-glucopyranoside （3）, （±）-catechin （4）, catechin-3-O- β-D-glucopyranoside （5）, catechin-5-O-β-D-glucopyranoside （6）, 1,3-bis-（4-hydroxy-3,5-dimethoxyphenyl）-1,3-propanediol （7）, （R）-（＋）-chaulmoogric acid （8）, friedelin （9）, uracile （10）, benzoic acid （11）, vaniUic acid （12）, and 4-hydroxybenzoic acid （13）. Conclusion All the compounds described above were isolated from this genus for the first time.目的对南岭柞木Xylosma controversum Clos茎的化学成分进行研究。方法应用各种色谱方法分离,应用波谱技术确定结构。结果分离鉴定了13个化合物,分别是:(-)-丁香树脂酚(1),丁香树脂酚-4-O-β-D-葡萄糖苷(2),丁香树脂酚-4,4'-O-β-D-双葡萄糖苷(3),(±)-儿茶素(4),儿茶素-3-O-β-D-葡萄糖苷(5),儿茶素-5-O-β-D-葡萄糖苷(6),1,3-bis(4-hydroxy-3,5-dimethoxyphenyl)-1,3-propanediol(7),(R)-(+)-大风子油酸(8),木栓酮(9),尿嘧啶(10),苯甲酸(11)香草酸(12),对羟基苯甲酸(13)。结论以上化合物均为首次从柞木属植物中分离得到。

关 键 词：FLACOURTIACEAE Xylosma controversum Chemical constituents 

分 类 号：R284.1[医药卫生—中药学]