高血压、高脂血症及糖代谢异常与肥胖的聚集现象  

The Clustering of Hypertention, Hyperlipidemia and Hyperglycemia with Obesity

作　　者：王震震[1] 钱卫冲[1] 王海燕[1] 杜福昌[1] 张仕清[1] 朱杰[1] 戴振华[1] 

机构地区：[1]南京医科大学第一附属医院心脏科

出　　处：《南京医科大学学报（自然科学版）》1997年第3期213-216,共4页Journal of Nanjing Medical University(Natural Sciences)

摘　　要：采用典型相关分析及单因素方差分析，在江苏农村自然人群中探讨肥胖与高血压、高脂血症及糖代谢异常的聚集现象，并寻找与这种聚集现象关系最密切的人体测量指标。典型相关分析结果表明：人体测量指标与代谢性指标相关（典型相关系数为０．３４～０．４８）；人体测量指标中体重指数（ＢＭＩ）的贡献最大，与代谢变量的相关性最密切；代谢变量中男性血脂、女性血压贡献最大，与人体测量变量相关最密切的是血压；单因素方差分析表明，ＢＭＩ受代谢变量危险性分组的影响最大。因此认为，体重指数是本组人群中肥胖与心血管危险因素聚集的最有价值的临床指标；血压是受肥胖影响最大的心血管危险因素。Using canonical correlation analysis and one way analysis of variance the relation between sets of anthropometric and metabolic variables was explored in free living individuals of Jiangsu rural areas. The objectives of these analyses are to determine the degree to which hypertention, hyperlipidemia and hyperglycemia cluster together, and to determine which clinical measure of obesity is most closely associated with such clustering. Canonical correlations were statistically significant between anthropometric and metabolic variables in all sex age specific groups. Standardized canonical coefficients from canonical analyses suggest that the weight for body mass index (BMI) is highest and positive in all sex age groups except for older group in men. Of the anthropometric variables, BMI consistently demonstrates the highest loading values. Of the metabolic variables the loading of blood pressure is generally the largest. BMI ranks most affected by the risk categorization. These analyses demonstrate significant clustering of hypertention, hyperlipidemia, hyperglycemia in individuals with obesity. It indicates that BMI is the single and simple measure of obesity most highly correlated with blood pressure.

关 键 词：高血压 高血脂病 糖代谢异常 肥胖 体重 

分 类 号：R544.1[医药卫生—心血管疾病] R589.2[医药卫生—内科学]