抗抑郁治疗对高血压并发抑郁症患者康复的影响  

The Influence of Anti-depression Therapy on Rehabilitation of the Primary Hypertension Patients Complicated With Depression

作　　者：王文清[1] 徐丽梅[1] 李玲[1] 李丰[1] 李燕玉[1] 

机构地区：[1]空军总医院康复科,北京100036

出　　处：《中国康复》2007年第5期326-327,共2页Chinese Journal of Rehabilitation

摘　　要：目的:探讨抗抑郁治疗对原发性高血压并发抑郁症患者康复的影响。方法:原发性高血压并发抑郁症患者102例,分为干预组60例和对照组42例,均服用洛汀新降压治疗;干预组加服罗拉西泮并配合康复治疗。结果:治疗6个月后,干预组汉密尔顿抑郁量表评分、收缩压及舒张压均显著低于治疗前及对照组(P<0.05),且并发有糖尿病和高脂血症的患者治疗效果也明显优于对照组(P<0.05),其心脑血管急性事件的发生率低于对照组。结论;抗抑郁治疗可以缓解原发性高血压病患者的抑郁状态,提高降压效果,改善血糖及血脂代谢,降低心脑血管急性事件的发生。Objective： To discuss the influence of anti-depression therapy on rehabilitation of the primary hypertension patients complicated with depression. Methods： 102 primary hypertension patients assessed by HRSD （Hamilton Rating Scale for Depression） were divided into 2 groups： control group （42） treated with lotensin （10 mg/day）, and antidepression group （60） treated with lotensin （10 mg/day）, lorazepam 2--3 mg/day and psychological nursing. The results of HRSD scores, systolic and diastolic pressure after treatment for 25 weeks were compared with those before therapy. Results： The results of HRSD scores, systolic and diastolic pressure in anti-depression group were lower remarkably than those in control group （P〈0.05）. The therapeutic effects for complicated diabetes and hyperlipidemia in anti-depression groups were superior to those of control group （P〈0.05）. The emergent onset of heart and brain diseases in anti-depression group was less than that in control group. Conclusion： Anti-depression therapy can relieve depression of the primary hypertension patients, improve the effects of anti-hypertension and metabolism of blood sugar and lipid, and lower the onset of heart and brain diseases.

关 键 词：原发性高血压 抑郁症 康复 

分 类 号：R49[医药卫生—康复医学] R544.1[医药卫生—临床医学]