血清瘦素、血脂、C-反应蛋白与冠心病发病的相关性研究  

The study of the relation about blood Leptin,blood lipid,serum C-reaction protein and coronary artery disease

作　　者：王同成[1] 张好[1] 唐元升[2] 

机构地区：[1]济南市第三人民医院,山东省250101 [2]山东省立医院

出　　处：《中国心血管病研究》2007年第11期830-830,832,共2页Chinese Journal of Cardiovascular Research

摘　　要：目的研究血清瘦素、血脂、C-反应蛋白水平与冠心病发病的相关性。方法被研究者共130例,分冠心病组和非冠心病组,检测他们的瘦素、血脂和CRP,进行统计学计算。结果冠心病患者的血清瘦素水平明显高于非冠心病患者[(8.84±4.99)ng/ml和(5.81±3.30)ng/ml,P<0.01)];两组血清CRP水平比较差异有统计学意义[(6.12±8.79)mg/L和(2.43±0.93)mg/L,P<0.01],部分血脂水平两组间差异有统计学意义。结论血清瘦素、CRP水平与冠心病发病密切相关,检测血清中瘦素、CRP水平可作为预测冠心病的良好指标。Objective To investigate the relevance among blood Leptin,blood lipid,serum CRP and CHD. Methods 130 cases were divided into the CHD group and the non-CHD groups, examined their blood Leptin, lipid and CRP level, carried on statistics computation. Results The CHD patient＇s blood Leptin level was obviously higher than the non-CHD patients [ （8.84±4.99）ng/ml vs （5.81±3.30）ng/ml,P〈0.01）]. Two groups of blood serums CRP level was obvious difference[ （6.12±8.79）mg/L vs （2.43±0.93）mg/L,P〈0.01） ], partial blood lipid level during two groups was obvious difference. Conclusion Blood Leptin level, serum CRP level is closely associated with CHD, Detecting the Leptin level,CRP level is a good method to pre-diagnosing CHD.

关 键 词：瘦素 脂类和降血脂药 C-反应蛋白质 冠状动脉疾病 

分 类 号：R541.4[医药卫生—心血管疾病]