支气管舒张试验在0～6岁儿童喘息性疾病中的应用  

Application of bronchodilation test by tidal breathing in 0～6 year old children with airway hyper-responsive diseases

作　　者：何金根[1] 潘家华[1] 计明红[1] 陶松雪[1] 

机构地区：[1]安徽医科大学附属省立医院,合肥230001

出　　处：《临床肺科杂志》2007年第12期1357-1358,共2页Journal of Clinical Pulmonary Medicine

摘　　要：目的利用潮气呼吸法进行儿童的支气管舒张试验,探讨其在0～6岁儿童喘息性疾病中的应用价值。方法2006年4～11月就诊于安徽医科大学附属省立医院儿科门诊及住院的儿童喘息性疾病244例,以沙丁胺醇作为支气管舒张药物,用潮气呼吸法分析评价小年龄喘息性疾病儿童吸入药物前后肺功能的变化,以探讨支气管舒张试验在该年龄段的应用价值。结果(1)吸入支气管舒张剂前后,以达峰时间比(TPTEF/TE)和达峰容积比(VPEF/VE)任意一个改善率≥15%为阳性标准,肺功能异常组阳性率明显高于正常组。(2)吸入支气管舒张药物,肺功能差值为负值率正常组明显高于异常组。(3)肺功能异常组各年龄段间支气管舒张试验阳性率无明显差异。结论支气管舒张试验在肺功能异常时应用较正常时更有价值。Objective To evaluate the application of bronchodilation test in tidal breathing of young children with airway hyperresponsive disease. Methods 244 children who saw doctor （because they were coughing with wheeze） at the Affilicated Provincial Hospital of Anhui Medical University, aged 8 - 73 months. The were classified into two groups： one group was normal pulmonary function （n = 93 ）, one group was abnormal pulmonary function （n = 151 ）. Each group received salbutamol. Tidal breathing parameters were obtained before and after aerosol inhalation to evaluate the effects of drugs. We evaluated the change of two groups of tidal breathing parameters. Results （ 1 ） Afer inhaling the drugs, if we used rises TPTEF/TE ≥ 15% or VPEF/VE rises ≥ 15% as the diagnostic standard, the positive rate of abnormal pulmonary function groups is higher than that of normal groups. （2） The negative value rate of abnormal pulmonary function groups is lower than that of normal groups （3） there were no differences in the positive rate of the abnormal pulmonary function groups in each one year. Conclusion We suggest that the applied value of bronchodilation test by tidal breathing in abnormal function is better than that of normal function of young children with airway hyper-responsive disease.

关 键 词：潮气呼吸 支气管舒张试验 儿童 

分 类 号：R725.6[医药卫生—儿科]