中药淫羊藿主要资源种类药材质量的系统研究  

Systematic studies on quality of main species of Herba Epimedii

作　　者：裴利宽[1] 黄文华[1] 何天谷 郭宝林[1] 

机构地区：[1]中国医学科学院中国协和医科大学药用植物研究所,北京100094 [2]贵州省印江县杨柳乡卫生院,贵州印江555212

出　　处：《中国中药杂志》2007年第21期2217-2222,共6页China Journal of Chinese Materia Medica

基　　金：国家自然科学基金项目(30270101)

摘　　要：目的:为有效实现淫羊藿药材质量控制,考察药典中规定的淫羊藿Epimedium brevicornu,箭叶淫羊藿E. sagittatum,柔毛淫羊藿E. pubescens,朝鲜淫羊藿E. koreanum和巫山淫羊藿E. wushanense等5个种,以及《贵州省中药材、民族药材标准》收载的粗毛淫羊藿E. acuminatum,天平山淫羊藿E. myrianthum,黔岭淫羊藿E. leptorrhizum3个种,以及贵州省作为巫山淫羊藿使用的拟巫山淫羊藿E. pseudowushanuse共9个主要资源种类的药材质量情况。方法:采用HPLC,UV测定共102份不同产地的上述9种淫羊藿药材样本的淫羊藿苷、总黄酮含量,并测定了以淫羊藿苷为参照的朝藿定A,B,C和淫羊藿苷(简称淫羊藿多苷,ABCI)4种成分的总量。结果和结论:以药典5个品种样品计,仅约有30%的样本淫羊藿苷含量达到药典标准,本研究提出以淫羊藿多苷的总量不低于1.3%,总黄酮含量不低于5.0%作为淫羊藿药材质量控制指标,并对各品种进行了质量评价,提出这些品种作为国家标准的参考意见。Objective： To achieve the quality control of Herba Epimedii, and to evaluate the quality of medical materials of the 8 official species including the 5 species recorded in ＇ Chinese Pharmacopoeia＇ including Epimedium brevicornum, E. sagittatum, E. pubescens, E. koreanum and E. wushanense, and the 3 other species （ E. acuminatum, E. myrianthum, E. leptorrhizum ） recorded in ＇ Guizhou Quality Criteria for Traditional Chinese Medical Material and Nationality Medical Material＇ , and E. psetMowushanuse （new speccies） which is used as E. wushanense for a long time. Method： The contents of ieariin and total flavonoids of 102 samples of 9 officinal species of Herba Epimedii were determined by HPLC and uv, respectively. Result and Conclusion： The contents of icariin in about 30% of the samples of the 5 species recorded in ＇ Chinese Pharmacopoeia＇ were lower than 0. 5%, which is acceptable quality recorded in ＇ Chinese Pharmacopoeia＇. Refering the literatures, we suggested the total contents of epimedin A, B, C and icariin （epimedium multi-glycosides,ABCI） should be established as a new standard instead of the content of icariin. The content of total flavonoids ,not less than 5.0%, and ABCI, not less than 1.3%, could be used to evaluate the quality of the above medical materials efficiently.

关 键 词：淫羊藿药材 淫羊藿多苷 淫羊藿苷 HPLC 总黄酮 UV 质量控制 

分 类 号：S567.239[农业科学—中草药栽培]