N-(5-巯基-1，3，4-噻二唑-2-基)-N'-取代苯甲酰基脲与取代的苯氧乙酰基脲的合成与生物活性  

Synthesis and Biological Activity of N-(5-Mercapto-1,3,4-thiadiazol-2-yl)-N'-(un)substituted Benzoylureas and (Un)substituted Phenoxyacetylureas

作　　者：陈传兵[1] 张正文[1] 杜敏[1] 王胜[1] 汪焱钢[1] 

机构地区：[1]华中师范大学化学学院

出　　处：《有机化学》2007年第11期1444-1447,共4页Chinese Journal of Organic Chemistry

基　　金：国家自然科学基金(No.20072009)资助项目

摘　　要：通过2-氨基-5-巯基-1,3,4-噻二唑与取代苯甲酰基异氰酸酯及取代苯氧乙酰基异氰酸酯反应,合成了21种新的取代苯甲酰基脲与取代苯氧乙酰基脲,其结构用红外光谱、核磁共振氢谱和元素分析进行了确证,初步的生物活性测定试验表明,部分目标化合物具有良好的植物生长调节活性.Twenty-one new （un）substituted benzoylureas and （un）substituted phenoxyacetylureas have been synthesized by the reaction of 2-amino-5-mercapto-1,3,4-thiadiazole with （un）substituted benzoyl isocyanates and （un）substituted phenoxyacetyl isocyanates, respectively, and their structures were confirmed by IR, ^1H NMR spectra and elemental analysis. The preliminary biological activity tests showed that some of the title compounds had good activity as plant growth regulators.

关 键 词：取代苯甲酰基脲 取代苯氧乙酰基脲 1 3 4-噻二唑 合成 生物活性 

分 类 号：TQ450.1[化学工程—农药化工]