我院224例药品不良反应报告分析  

Analysis of 224 Cases of Adverse Drug Reactions in Our Hospital

作　　者：朱定春[1] 莫陵[1] 范平平[1] 

机构地区：[1]南京医科大学附属南京第一医院,江苏南京210006

出　　处：《中国药业》2007年第21期36-37,共2页China Pharmaceuticals

摘　　要：目的分析探讨药品不良反应(ADR)相关因素,为临床合理用药提供参考。方法对医院2006年1～12月收集的224例ADR报告进行分类统计并分析。结果224例ADR中,抗感染药物引起的ADR159例(占70.98%),中成药制剂26例(占11.61%);ADR累及器官以皮肤及附件最为常见,占总数的58.93%(132例),其次是消化系统损伤;较严重的ADR有4例,占1.79%;女性ADR高于男性,≥60岁患者ADR发生率高于一般人群;静脉给药引起的ADR最多,占总例数的79.46%(178例)。结论ADR的发生原因诸多,表现多样,加强ADR监测、合理用药是降低ADR发生的重要措施。Objective To analyse the factors related to adverse drug reaction （ADR） and to provide reference for using the drugs correctly. Methods To perform statistical analysis for 224 ADR reports collected from January 2006 to December 2006 in the hospital. Results Among 224 ADR cases, 159 （70.98% ） cases were caused by anti-infection drugs, Chinese traditional medicines accounted for 11.61% （26 cases）. The most common ADR manifestations were the damages of the skin and its adjunct, which accounted for 58.93% （132 cases）, Next is the damages of digest system. There were 4 serious ADR cases, which accounted for 1.79%. The ADR incidence rate of female was higher than that of male. The ADR incidence of old people over 60 years were higher than those people under 60 years. Most ADR cases were caused by infusion drugs, which accounted for 79.46% （178 cases）, Conclusion There are many factors causing ADR. Observing carefully and using the drugs correctly are the main methods reducing the ADR.

关 键 词：药品不良反应 统计分析 合理用药 

分 类 号：R969.3[医药卫生—药理学]