3-仲烃基斯德酮的合成  

THE SYNTHESIS OF 3-SEC- HYDROCARBYLSYDNONES

作　　者：王宏志[1] 吴永仁[1] 尹承烈[1] 

机构地区：[1]北京师范大学化学系,北京100875

出　　处：《北京师范大学学报（自然科学版）》1997年第1期96-98,共3页Journal of Beijing Normal University(Natural Science)

摘　　要：报导了3-仲烃基斯德酮的合成，其方法是将酮类化合物与甘氨酸乙酯缩合，再将所得的Schiff碱经还原、水解、亚硝化及环化，得到3-仲烃基斯德酮．后者与溴反应，获得3-仲烃基-4-溴斯德酮．它们的结构经元素分析，IR，1HNMR所证实．The title compounds which has the general structure (R=Menthyl-, p Cl-C6H4CHCH3, α-naphthylCHCH3) were synthesized by following route. Using ketonesas starting material condensed with ethyl glycinate to obtain Schiff bases, then by reductionwith NaBH4, hydrolysis, nitrosation and cydisation obtain 3 - sec- hydrocarbylsydnone.Bromination of 3 -sec- hydrocarbylsydnone were also studied. Their structures are deduced byelemental analysis. IR and 1HNMR.

关 键 词：斯德酮 仲烃基斯德酮 合成 席夫碱 MANNICH反应 

分 类 号：O626.1[理学—有机化学]