鼻咽癌适形调强放疗减少脊髓和腮腺受量的物理剂量研究  

Effectively sparing spinal cord and parotid by IMRT to NPC patient

作　　者：刘翔宇 刘俐 孙世良 何光雷 吴丽华 Liu Xiangyu;Liu Li;Sun Shiliang;et al（Department of Radiation Oncology;Chongqing Cancer Hospital;Chongqing 400030;China）

机构地区：重庆市肿瘤医院,重庆400030

出　　处：《中国保健》2006年第07X期1-3,共3页Chinese Health Care

摘　　要：目的：评价鼻咽癌常规放疗、适形放疗、适形调强放疗的PTV、脊髓和腮腺受量。方法：应用Eclipse治疗计划系统,对同一病人采用三种治疗的计算方法,比较PTV、脊髓和腮腺剂量体积关系。结果：三种治疗方法PTV均在高剂量区域内,但采用适形调强放疗时重要器官受量明显减少。结论：鼻咽癌适形调强放疗能较好地适形照射肿瘤体积,有效保护邻近重要感器官,提高生存质量。Objective：Evaluation of dose distribution in PTV,spinal cord and parotid for NPC with classical radiation therapy planning or three dimensional conformal radiation therapy（3DCR）planning or intensity modulated radiation therapy（IMRT）planning.Methods：Using Eclipse planning system,a same nasopharyngeal carcinoma patient was treated by three different methods such as classical radiation therapy or the three dimensional conformal radiation therapy or the intensity modulated radiation therapy to compare the relationship among the value of dose volume of tumor and parotid as well as spinal cord.Results：In the three methods,PTV is all in the high dose area.And the mean dose and volume to critical structure is lower when IMRT is used.Conclusion：The treatment of NPC by IMRT can have more conformal dose distribution to volume and effectively sparing critical structures and improve quality of life.

关 键 词：鼻咽癌 调强放疗 脊髓 腮腺 

分 类 号：R815.2[医药卫生—放射医学;医药卫生—临床医学]