缬沙坦贝那普利对急性心肌梗塞后左心室重构的影响  

Influence of Losartan and Ramipril to Left Ventricle Reconstruction after Acute Myocardial Infarction.

作　　者：张道进 郑琼 Zhang Dao, Jin Zheng Qiong, （Dapartment of Internal Medicine, Jiangmen Second People＇ s Hospital, Jiangmen, Guang dong Province, 529000, China. ）

机构地区：江门市第二人民医院,广东江门529000

出　　处：《中国保健》2006年第09X期11-12,共2页Chinese Health Care

摘　　要：目的：了解缬沙坦及贝那普利对急性心肌梗塞（AUl）患者左心室重塑的影响。方法：急性心肌梗塞患者54例,按治疗不同分为3组：缬沙坦组（n=18）、贝那普利组（n=20）和对照组（n=16）,观察入院之初及6个月后用二维超声测量的左室重量.结果：观察组平均心肌重量低于对照组（P〈0.05）。结论：缬沙坦、贝那普利能有效地控制急性心肌梗死后左室重构。贝那普利组咳嗽发生率25%,而缬沙坦组无1例咳嗽发生。结论：缬沙坦、贝那普利对AMI患者具有相似的抗左心室重塑效应,缬沙坦耐受性更好。Objective： To understand the influence of Losartan and Ramipril o left ventricle reconstruction after acute myocardial infarction （AMI）.Methods： 54 cases of AMI were divided three groups according to different treatment： Losaran group（n = 18）, Ramipril group（n = 20） and control group（n = 16）, to observe left ventricle weight measured by two dimensions ultrasonic in admitted to hospital and after 6 months, Result： The average cardiac muscle weight in observtion group was under control group（ P 〈 0.05 ）. Conclusion： Losartan and Ramipril oroups could control effectively left ventricle reconstruction after AMI. Coughing chance in Ranipril group was 25%, but no cough happening in Losartan group. Losartan and Ramipril had alike effect of resisting left ventricle reconstruction to AMI patients Losartan tolerance was better.

关 键 词：心肌梗塞 左心室重塑 缬沙坦 贝那普利 

分 类 号：R972.4[医药卫生—药品;医药卫生—药学]