皮肤黏膜淋巴结综合征192例临床分析  

Analysis on Clinical Data of 192 Children with Mucocutaneous Lymphnode Syndrome

作　　者：谢红[1] 李熙鸿[2] 

机构地区：[1]四川省中西医结合医院儿科,四川成都610041 [2]四川大学华西第二医院儿科,四川成都610041

出　　处：《海南医学》2007年第11期48-49,共2页Hainan Medical Journal

摘　　要：目的探讨川崎病(KD)尤其是非典型KD的诊断及临床表现特点。方法对我院典型KD131例和非典型KD61例临床资料进行回顾性分析及总结。结果192例KD的男女比例为1.87∶1,其中4岁以下发病占76.6%;非典型KD占31.8%。典型和非典型KD两组发病在性别、年龄、实验室检查方面没有明显差异(P>0.05);在皮疹、结膜充血、淋巴结肿大、脱屑与硬肿及心脏冠状动脉损害方面,典型KD组与非典型KD组比较有显著性差异(P<0.01)。结论KD发病中非典型表现发生率有逐渐增多趋势,非典型KD冠状动脉损害发生率低于典型KD。Objective To study the clinical characteristics and diagnosis of children with Kawasaki disease （KD）, especially atypical cases. Methods Clinical data of 131 typical and 61 atypical cases of KD were retrospectively analyzed （e.g., conjunctival injection, enlarged lymph glands, skin rash, etc. ）. Results A dight male predominance is apparent（1.87：1） in 131（68.2%） typical and 61（31.8%） atypical cases of KD, and 76.6% of cases occurred in children younger than 4 years of age. Significant difference （P〈0.01） was found between typical and atypical KD in red rash, conjunctival injection, enlarged lymph glands, skin rash, peeling and swelling of the extremities and damage to coronary arteries, but not in sex, age and, laboratory test （P〉0.05）. Conclusions The incidence of atypical cases of KD seems to be with an ascending trend year by year, but the incidence of coronary problem is lower in atypical cases than in typical cases.

关 键 词：川崎病 非典型川崎病 儿童 冠状动脉损害 

分 类 号：R725[医药卫生—儿科]