Evaluation of the effect and profitability of gene-assisted selection in pig breeding system  

作　　者：LI Ya-lan ZHANG Qin CHEN Yao-sheng 

机构地区：[1]College of Animal Science, South China Agricultural University, Guangzhou 510642, China [2]College of Animal Science and Technology, China Agricultural University, Beijing 10094, China [3]College of Life Science, Sun Yat-sen University, Guangzhou 510275, China

出　　处：《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》2007年第11期822-830,共9页浙江大学学报（英文版）B辑（生物医学与生物技术）

基　　金：Project (No. 30300249) supported by the Natural Science Foundationof Guangdong Province, China

摘　　要：Objective:To evaluate the effect and profitability of using the quantitative trait loci (QTL)-linked direct marker (DR marker) in gene-assisted selection (GAS). Methods: Three populations (100, 200, or 300 sows plus 10 boars within each group) with segregating QTL were simulated stochastically. Five economic traits were investigated, including number of born alive (NBA), average daily gain to 100 kg body weight (ADG), feed conversion ratio (FCR), back fat at 100 kg body weight (BF) and intramuscular fat (IMF). Selection was based on the estimated breeding value (EBV) of each trait. The starting frequencies of the QTL's favorable allele were 0.1, 0.3 and 0.5, respectively. The economic return was calculated by gene flow method. Results: The selection efficiency was higher than 100% when DR markers were used in GAS for 5 traits. The selection efficiency for NBA was the highest, and the lowest was for ADG whose QTL had the lowest variance. The mixed model applied DR markers and obtained higher extra genetic gain and extra economic returns. We also found that the lower the frequency of the favorable allele of the QTL, the higher the extra return obtained. Conclusion: GAS is an effective selection scheme to increase the genetic gain and the eco- nomic returns in pig breeding.Objective： To evaluate the effect and profitability of using the quantitative trait loci （QTL）-linked direct marker （DR marker） in gene-assisted selection （GAS）. Methods： Three populations （100, 200, or 300 sows plus 10 boars within each group） with segregating QTL were simulated stochastically. Five economic traits were investigated, including number of born alive （NBA）, average daily gain to 100 kg body weight （ADG）, feed conversion ratio （FCR）, back fat at 100 kg body weight （BF） and intramuscular fat （IMF）. Selection was based on the estimated breeding value （EBV） of each trait. The starting frequencies of the QTL＇s favorable allele were 0.1,0.3 and 0.5, respectively. The economic return was calculated by gene flow method. Results： The selection efficiency was higher than 100% when DR markers were used in GAS for 5 traits. The selection efficiency for NBA was the highest, and the lowest was for ADG whose QTL had the lowest variance. The mixed model applied DR markers and obtained higher extra genetic gain and extra economic returns. We also found that the lower the frequency of the favorable allele of the QTL, the higher the extra return obtained. Conclusion： GAS is an effective selection scheme to increase the genetic gain and the economic returns in pig breeding.

关 键 词：SWINE Gene-assisted selection （GAS） Selection efficiency Extra retums 

分 类 号：Q78[生物学—分子生物学] TP31[自动化与计算机技术—计算机软件与理论]