尼群地平对猪冠状动脉舒缩活动和主动脉平滑肌细胞增殖的影响  

Effects of Nitrendipine on Activity of Coronary Artery and Proliferation of Aortic Smooth Muscle Cell in Porcine

作　　者：涂玉林[1] 杨小毅 万载阳 周元芳 

机构地区：[1]衡阳医学院心血管病研究所,衡阳421001

出　　处：《中国动脉硬化杂志》1997年第1期49-51,共3页Chinese Journal of Arteriosclerosis

摘　　要：采用离体血管实验观察到尼群地平能使冠状血管松弛，这件松弛作用与血管内皮完整与否无关．同时．我们还观察到，尼群地平可抑制培养的动脉平滑肌细胞的增殖．提示尼群地平舒张血管和抑制血管平滑肌增殖，可能是其抗实验性动脉粥样硬化作用的重要机制之一．Aim This study was searched for active mechanism of nitrendipine that prevents and treats atheroscle-rosls.Method The experiments were performed in coro-nary arterial rings of Porcine. Results Nitrendipine inhibited proliferation of cul-tured vascular smooth muscle cell witb M IT colori-nelrc assay in porcine.Chadusio.s Nitrendipine may play an important role on antiatherosclerosis

关 键 词：尼群地平 冠状动脉 血管平滑肌细胞 

分 类 号：R972.4[医药卫生—药品] R543.5[医药卫生—药学]