阿奇霉素致血尿和蛋白尿2例  

Azithromycin-induced hematuria and proteinuria in two cases

作　　者：李辉[1] 张永东[1] 肖云彬[1] 罗继名[1] 

机构地区：[1]郴州市第一人民医院药剂科,湖南郴州423000

出　　处：《药物不良反应杂志》2007年第5期369-370,共2页Adverse Drug Reactions Journal

摘　　要：1对27岁夫妇,均因化脓性扁桃体炎静脉给予阿奇霉素0.2g。次日,2名患者均出现全程肉眼血尿。尿常规:RBC分别为(+)、(┼┼┼),尿蛋白均为(┼┼┼),肝肾功能及ASO正常,泌尿系统B超检查未见异常。立即停用阿奇霉素,给予酚磺乙胺、维生素C及补液治疗,尿液逐渐转清,第8天尿常规恢复正常。随访1月,尿常规持续正常。A 27-year-old couple with suppurative tonsillitis received IV azithromycin 0.2 g. The next day, both of them presented with gross hematuria in the whole process of urination. Urinalysis revealed their presence of RBC （ ＋ ） and （＋＋＋） respectively, and protein（＋＋＋ ）.Their liver function, renal function, and ASO were normal. A B-ultrasonic examination found no abnormality in their urinary system. Azithromycin was ceased immediately. After treatment with etamsylate, vitamin C, and fluid replacement, their urine became clear gradually. During 1 month of follow-up, their urine routine maintained normalization.

关 键 词：阿奇霉素 血尿 蛋白尿 

分 类 号：R595.3[医药卫生—内科学]