激光、机械心肌打孔血运重建机制的探讨及比较  

Mechanisms and Comparison of Transmyocardial Revascularization by Laser or Mechanical Means

作　　者：赵健[1] 王颖[1] 刘晓程[1] 

机构地区：[1]中国医学科学院中国协和医科大学泰达国际心血管病医院心外科,天津300457

出　　处：《心血管病学进展》2007年第6期927-930,共4页Advances in Cardiovascular Diseases

基　　金：天津市科技发展计划项目资助(05YFGZSF02900)

摘　　要：经皮冠状动脉介入和冠状动脉搭桥术,作为重要的心肌血运重建方式,挽救了大量冠心病患者的生命;但是,针对弥漫性血管病变患者,上述两种治疗方法受到了很大的限制。基于室腔-孔道-心肌窦状隙梯度灌注理论的心肌打孔术,已由最初的机械针刺途径发展为目前的激光方式,为大量冠心病患者的治疗带来了曙光。现就二者促进血运重建、改善心肌灌注、缓解心绞痛症状的机制作一文献综述及比较。Percutaneous coronary intervention （ PCI） and coronary artery bypass grafting （ CABG）, as important revascularization treatments, have cured many patients with coronary heart disease. However, growing numbers of patients with diffuse stenoses are not amenable to PCI and CABG. Transmyocardial revascularization, based on the hypothesis of gradient perfusion of ventricle chamber （ channel） sinusoid, has developed from its origins in acupuncture to a process using laser devices. This review discusses and compares the mechanisms of transmyocardial laser or acupuncture revascularization, which improve myocardial perfusion and relieve angina symptoms.

关 键 词：冠心病 心肌血运重建 打孔 

分 类 号：R541.4[医药卫生—心血管疾病] R454.2[医药卫生—内科学]