辅助抗生素治疗宫颈癌前病变并发幽门螺杆菌感染的疗效观察  

Investigation of the effects of antibiotic assistant treatment on cervical pre-cancer combining helicobacter pylori infection

作　　者：余红[1] 韩淑英[1] 张萍[2] 陈素兰[2] 张桂荣[2] 

机构地区：[1]华北煤炭医学院基础医学部药理学教研室,河北唐山063000 [2]华北煤炭医学院附属医院

出　　处：《华北煤炭医学院学报》2007年第6期765-766,共2页Journal of North China Coal Medical College

摘　　要：①目的探讨辅助抗生素治疗对宫颈癌前病变并发幽门螺杆菌(Hp)感染的治疗效果。②方法采用快速Hp尿素酶检测法筛选宫颈癌前病变的相关病例,用阴道镜和组织病理学进行诊断证实。对各类宫颈癌前病变创伤性治疗的同时,规范采用甲硝唑治疗,观察幽门螺旋杆菌阳性率的改变和临床表现的变化。③结果Hp感染与宫颈癌前病变发展为宫颈癌有相关性;除了手术治疗外,规范的甲硝唑治疗可以降低Hp感染的阳性发生率,同时,可以对宫颈癌起病因学治疗作用。④结论辅助抗生素治疗对宫颈癌前病变并发Hp感染的患者,可以起到消除潜在癌变的诱因和提高疗效的作用。Objective To investigate the effects of antibiotic assistant treatment on cervical pre - cancer combining helicobacter pylork Methods The cases of cervical pre - cancer were chose with rapid biopsy urease test and proved with vaginoseopc and the tissue pathology. After cervical pre - cancer was treated by operation and Metronidazole, the positive rate of H, pylori infection and clinical changes were observed. Results Cervical cancer was related with Helicobacter pylori infection and cervical pre - cancer pathological changes. Besides operation, the positive rate of Hehcobacter pylori infection was decreased and cervical cancer in etiology was treated by Metronidazole. Conclusion The inducement of cancer changes was eliminated and the treatment effect was improved by antibiotic assistant treatment in cervical pre -cancer combining Helicobacter pylori infection,

关 键 词：幽门螺杆菌 宫颈癌 阴道镜 甲硝唑 

分 类 号：R711.32[医药卫生—妇产科学]