抗白斑综合征病毒(WSSV)感染途径研究进展  

Developing strategies available for resistance to white spot syndrome virus (WSSV)

作　　者：罗展[1] 黄倢[2] 周丽[1] 

机构地区：[1]中国海洋大学生命科学与技术学部,青岛266003 [2]农业部海洋渔业资源可持续利用重点开放实验室中国水产科学研究院黄海水产研究所,青岛266071

出　　处：《海洋水产研究》2007年第5期116-122,共7页Marine Fisheries Research

基　　金：国家重点基础研究发展规划项目(G1999012002);国家自然科学基金项目(30271020)共同资助

摘　　要：白斑综合征病毒(White Spot Syndrome Virus,WSSV),是引起养殖对虾大规模死亡的病原。在过去的10年中,各国学者不断地寻找预防和控制WSSV感染的方法及途径。本文主要介绍了中和抗体与噬菌体展示单链抗体、免疫增强剂、重组蛋白疫苗和灭活疫苗、遗传育种、RNAi等几种方法的研究现状,为进一步开发抗WSSV药物和饵料,更有效地防治WSSV及相关科研提供参考。White Spot Syndrome Virus （WSSV） is one of the viral pathogens which could cause large-scale mortality in farmed shrimp. Various studies have been made on the strategies of prophylaxis and control of WSSV infection during the past decade. This paper mainly presents the research status in quo of hot strategies, including neutralizing antibody and phage display ScFv antibody, immunostimulants, vaccines based on recombinant proteins or inactived WSSV, genetic selection, and RNA interfering, aiming at exploiting antiviral drugs and feeds and providing a useful reference for the disease control and the interrelated research.

关 键 词：白斑综合征病毒 抗病毒 途径 

分 类 号：S945.46[农业科学—水产养殖]