巨细胞病毒感染致婴儿听力损害早期干预初探  

Initially Investigation of Early Intervention Therapy of the Hearing Impairment Due to Cytomegalovirus Infection in Infants

作　　者：万盛华[1] 黄雄 王倩[2] 曾习文[1] 张双红[1] 罗丽娟[1] 

机构地区：[1]江西省儿童医院消化内科,南昌330006 [2]江西省儿童医院神经电生理室,南昌330006

出　　处：《江西医学院学报》2007年第5期62-64,共3页Acta Academiae Medicinae Jiangxi

摘　　要：目的探讨以更昔洛韦为主综合早期干预巨细胞病毒（CMV）感染致婴儿听力损害的疗效。方法应用听觉脑干诱发电位（ABR）对CMV感染婴儿进行听力筛查及评估，对16例听力损害的患儿采用更昔洛韦抗病毒、营养脑细胞及听觉刺激法等综合早期干预治疗。结果疗程结束后3-6个月时复查脑干听觉诱发电位，治愈12例（75%），有效2例（12.5%），无效2例（12.5%），总有效率为87.5%。结论更昔洛韦为主的综合早期干预，对CMV感染引起的婴儿听力损害的疗效满意、安全，临床值得推广。Objective To investigate the curative effect of the early intervention therapy mainly combining with Ganciclove on the hearing impairment resulted from cytomegalovirus infection in infants. Methods Using the tools of auditory brain-stem response （ABR）,the hearing ability of infants with cytomegalovirus infection was screened and evaluated. Sixteen patients with hearing impairment were taken by the early intervention therapy combining with Ganciclove, ATP, COA nutrition of brain cell, stimulating sense of hearing and so on. Results After therapy termination and then 3-6 months later,auditory brain-stem response were investigated, 12 cases（75 %） were normal,2 cases （12. 5%）were effective, 2 cases（12.5 %） showed no effect. The total effective rate was 87.5 %. Conclusion This method is efficient and secure and it is good for clinical application.

关 键 词：巨细胞病毒感染 听力损害 脑干听觉诱发电位 更昔洛韦 早期干预 

分 类 号：R725.129.3[医药卫生—儿科]