贝那普利联合比索洛尔治疗充血性心力衰竭的疗效研究  

The clinical efficacy of Benazepril accompanied with Bisoprolol for treatment of congestive heart failure

作　　者：何月光[1] 何世利 赵先光[3] 张富娥[3] 迟伟[3] He Yueguang, He Shili ,Zhao Xianguang, Zhang Fue ,Chi Wei

机构地区：[1]湖南永州职业技术学院医学院,425006 [2]湖南道县人民医院,425300 [3]湖南省永州市人民医院,425006

出　　处：《中外健康文摘：临床医师》2007年第10期26-27,共2页

摘　　要：目的：探讨贝那普利联合比索洛尔治疗慢性充血性心力衰竭（CHF）的临床疗效。方法：128例CHF病人随机分为治疗组和对照组。治疗组68例给予贝那普利2．5～5mg，比索洛尔100～200mg／d；对照组60例给予地高辛、利尿剂、硝苯地平治疗。两组疗程6个月。观察治疗前后两组病人的临床症状、超声心动图心功能指标、6min步行距离的变化及不良反应。结果：治疗后治疗组临床总有效率为90．63％，对照组总有效率为68．75％，治疗前后相比两组LVEF、SV、CI、6min步行的距离均有显著改善（P〈0．01），治疗组LVEF、CI及6min步行距离的改善优于对照组。结论：贝那普利联合比索洛尔治疗CHF可以增强疗效。Objective： To study the clinical therapeutic efficacy of Benazepril accompanied with Bisoprolol for treatment congestive heart failure（CHF）. Method. Random controlled trial was employed. We divided 128 patient with CHF into the treatment group（n=68）and the control group（n=60）. The clinical therapeutic, efficacy. LVEF, SV, CI 6rain walk trial and adverse reactions were analyzed. Result： The clinical prognosis and LVEF, SV, CI, 6min walk trail of the patients in the two groups were all significantly ameliorated compared with those of the patient before treatment（P〈0.01）, improvement of symptoms in the treatment group was better than that in the control group. Conclusion.Benazepril accompanied with Bisoprolol possesses obvious effect in treating patient with CHF.

关 键 词：贝那普利 比索洛尔 充血性心力衰竭 

分 类 号：R541[医药卫生—心血管疾病;医药卫生—临床医学;医药卫生—内科学]