系统性红斑狼疮继发肺动脉高压的研究  

Research Progress of Pulmonary Hypertension in Systemic Lupus Erythematosus

作　　者：智淑清[1] 

机构地区：[1]内蒙古医学院附属医院内科,呼和浩特010050

出　　处：《医学综述》2007年第17期1318-1320,共3页Medical Recapitulate

摘　　要：系统性红斑狼疮(SLE)是一种病因不明的自身免疫性疾病,全身各器官或系统可同时或相继受累,发生一系列病理生理变化,部分患者可致肺动脉高压(PAH)。由于其临床表现非特异,病情进展快,治疗困难,一旦诊断PAH,2年病死率≥50%,因而越来越引起人们的重视。本文就近年来有关其发病机制、诊断及治疗的研究综述如下。Systemic lupus erythematosus is a autoimmune disease with unknown etiology,in which all organ or system of body can be involved simultaneously or one after another undergoing a series of pathophysiological changes,furthermore,pulmonary arterial hypertension can be found in parts of patients with this diseases.Becaude it has unspecific clinical feature,rapid progressive condition,difficult therapy,more than 50% in case fatality of two years once being diagnosed,more and more attention are being attracted from people.This article reviews study progresses about its pathogenesis,diagnosis and therapy.

关 键 词：系统性红斑狼疮 肺动脉高压 诊断 治疗 

分 类 号：R593.24[医药卫生—内科学] R543.2[医药卫生—临床医学]