心脉舒胶囊制备工艺的优选研究  

Optimum Selection of the Preparation Procedure of Xinmaishu Capsule

作　　者：肖莉[1] 

机构地区：[1]南京市鼓楼医院,南京210008

出　　处：《黑龙江医药》2007年第6期604-605,共2页Heilongjiang Medicine journal

摘　　要：目的:优选心脉舒胶囊最佳制备工艺.方法:以芍药苷提取率和干浸膏得率为考察指标,应用正交试验设计筛选心脉舒胶囊最佳制备工艺条件.结果:处方药材加水煎煮提取2次:第一次加10倍量水,煎煮1.5小时;第二次加8倍量水,煎煮1.5小时,提取液滤过,合并,浓缩至1.0g生药/ml,加95%乙醇调节含醇量至80%,充分搅拌,静置12小时.结论:优选的最佳制备工艺稳定可行.Objective：To choose the preparation procedure of Xinmaishu capsule. Methods：The optimal preparation process was selected with the orthogonal design. The extraction percentage of peoniflorin and the yield of extracts were used to evaluate the factor levels. Results ：The optimal preparation process was： extracted with water for 2 times, first 10 times amount, extracted 1.5h, then 8 times amount, extracted 1.5h. The optimal procedure of ethanol precipitation was 1.0g/ml, 80 % ethanol, laying up 12 hours. Conlusions ：This preparation condition is the best way.

关 键 词：心脉舒胶囊 正交试验 芍药苷 提取 醇沉 

分 类 号：R284[医药卫生—中药学]