彭泽贝母中二萜类成分  

Diterpenoids from bulbus of Fritillaria monanth

作　　者：刘红宁[1] 李飞[1] 罗永明[1] 朱卫丰[1] 颜冬梅[1] 黄兴发[1] 

机构地区：[1]江西中医学院,江西南昌330006

出　　处：《药学学报》2007年第11期1152-1154,共3页Acta Pharmaceutica Sinica

基　　金：国家自然科学基金重点项目(30160097).

摘　　要：为了研究彭泽贝母的化学成分。利用多种柱色谱方法进行分离纯化,根据光谱数据和理化性质进行结构鉴定。共分离并鉴定了6个对映-贝壳杉类二萜化合物:ent-kauran-15-en-17-ol(I),ent-kauran-15-en-3α,17-diol(II),鄂贝新醇(III),ent-kauran-16α,17-diol(IV),ent-kauran-3α,16α,17-triol(V),ent-16,17-epoxy-kauran-3α-ol(VI)。6个化合物均为首次从彭泽贝母中分得,其中ent-16,17-epoxy-kauran-3α-ol(VI)为新化合物。To study the chemical constituents of Vrittllaria monanttt Migo, tne constituents wetc separated and purified by column chromatography on silica gel, and the structures were identified by NMR, MS spectral data. Six compounds were isolated and identified as ent-kauran-15-en-17-ol（I）,ent-kauran-15-en-3α,17-diol（II）, fritillaziebinol （III）,ent-kauran-16α,17-diol（IV）,ent-kauran-3α,16α,17-triol（V）,ent-16,17-epoxy-kauran-3α-ol（VI）. All the compounds were isolated from this plant for the first time, and VI is named as ent-16,17-epoxy-kauran-3α-ol, which is a new compound.

关 键 词：彭泽贝母 化学成分 ent-16 17-epoxy-kauran-3α-ol 

分 类 号：R284.1[医药卫生—中药学]