多壁碳纳米管与甘草苷和异甘草苷的选择性吸附作用  

Selective adsorption of multi-walled carbon nanotubes with liquiritin and isoliquiritin

作　　者：韩博[1] 李晴暖[1] 吴胜伟[1] 李俊纲[1] 陈文[2] 李文新[1] 

机构地区：[1]中国科学院上海应用物理研究所纳米医药研究室,上海201800 [2]兵团教育部共建新疆特种植物药资源重点实验室,新疆石河子832002

出　　处：《药学学报》2007年第11期1222-1226,共5页Acta Pharmaceutica Sinica

基　　金：国家自然科学基金资助项目(10475109);国家重点基础研究发展计划资助项目(2006CB705605).

摘　　要：Selective adsorption of active ingredients liquiritin and isoliquiritin from Glycyrrhiza uralensis Fisch with multi-walled carbon nanotubes(MWNTs) has been studied.Distribution coefficients of liquiritin between ethanol solvent and r-MWNTs or o-MWNTs in 293K is 37.5 and 43.3,while the distribution coefficients of isoliquiritin between ethanol solvent and r-MWNTs or o-MWNTs is 717 and 1080,respectively.It was indicated that the distribution coefficient of isoliquiritin adsorbed by MWNTs was much larger than that of liquiritin,and oxidation treatment of MWNTs could obviously enhance their adsorption ability.The possible reasons that MWNTs can selectively adsorb isoliquiritin other than liquiritin were discussed on the bases of molecular structure of the active ingredients and their interaction with nanotubes.Selective adsorption of active ingredients liquiritin and isoliquiritin from Glycyrrhiza uralensis Fisch with multi-walled carbon nanotubes （MWNTs） has been studied. Distribution coefficients of liquiritin between ethanol so/vent and r-MWNTs or o-MWNTs in 293K is 37.5 and 43.3, while the distribution coefficients of isoliquiritin between ethanol solvent and r-MWNTs or o-MWNTs is 717 and 1080, respectively. It was indicated that the distribution coefficient of isoliquiritin adsorbed by MWNTs was much larger than that of liquiritin, and oxidation treatment of MWNTs could obviously enhance their adsorption ability. The possible reasons that MWNTs can selectively adsorb isoliquiritin other than liquiritin were discussed on the bases of molecular structure of the active ingredients and their interaction with nanotubes.

关 键 词：多壁碳纳米管 甘草苷 异甘草苷 选择性吸附 

分 类 号：O642[理学—物理化学]