传染性与分娩方式对HBV母婴垂直传播的影响  

Effect on HBV monther - infant transmission in infectiousness and labor presentation.

作　　者：陈静[1] 张平[1] 

机构地区：[1]天津市传染病医院,天津300192

出　　处：《现代保健（医学创新研究）》2007年第09X期8-9,共2页

摘　　要：目的探讨孕妇不同传染性与分娩方式对HBV母婴垂直传播的影响。方法将409例HBsAg阳性孕妇分为HBeAg阳性组与HBeAg阴性组，同时按照分娩方式分为剖宫产组与阴道分娩组，新生儿出生1小时内检测股静脉血，HBsAg阳性和（或）HBVDNA阳性为宫内感染。结果HBeAg阳性与HBeAg阴性两组感染率分别为17．5％和7．2％，两组比较有极其显著的差异（P〈0．01）。其中HBeAg阴性组阴道分娩与剖宫产分娩的感染率分别为14．7％和2．7％，差异具有统计学意义（P〈0．05）。结论HBeAg阳性母亲其新生儿HBV感染率显著高于HBeAg阴性母亲，HBeAg阴性组剖宫产分娩新生儿感染率低于阴道分娩。Objective To investigate the effect on HBV mother - infant vertically transmission in different infectiousness and labor presentation. Methods 409 pregnant women were positive of HBsAg,they were divided of HBeAg positive group and HBeAg negative group. And according to the labor presentation they were divided of abdominal delivery group and vaginal delivery group. Newborns examine femoral venous blood after birth one hour. HBsAg positive and （or） HBVDNA positive was infection. Results The mother - infants transmission rate of HBeAg positive group and HBeAg negative group different were 17.5% andT. 2%. The difference of the tow groups was significant （ P 〈 0.01 ）. HBeAg negative group＇s infection rate of vaginal delivery and abdominal delivery different were 14.7% and 2.7%. The difference of the two groups were significant（ P 〈0.05 ）. Conclusion The infection rate of newborns form HBeAg positive mothers is significantly higher than HBeAg negative mothers. HBeAg negative group＇s infection rate of newborns form cesarean section is lower than that form vaginal delivery.

关 键 词：传染性 分娩方式 乙型肝炎病毒 垂直传播 

分 类 号：R512.62[医药卫生—内科学]