陕西省大骨节病病情现状与相关因素调查  

Investigation of Kaschin-Beck disease status and associated factors in Shaanxi Province

作　　者：杨杰[1] 吕晓亚[1] 徐刚要[1] 陈平[1] 何新科[1] 

机构地区：[1]陕西省地方病防治研究所,西安710003

出　　处：《中国地方病学杂志》2007年第6期652-655,共4页Chinese Jouranl of Endemiology

基　　金：中央补助地方公共卫生专项资金地方病防治项目(2005)

摘　　要：目的进一步掌握陕西省大骨节病病情消长态势和相关环境因素对大骨节病发生、发展的影响,为今后大骨节病的防治决策提供依据。方法在陕西省大骨节病病区范围内分别选择了6个项目调查点和20个省级自设监测点。临床检查7～12岁儿童2568例。右手X线拍片1788例。采集项目点粮样600份和发样300份。测定粮硒、发硒及食粮(180份)T-2毒素水平,调查相关因素与病情的关系。结果全省23个病区县(区)26个调查点中,大骨节病临床Ⅰ度以上患者无检出,X线总检出率为1.29%;儿童发硒为(0.37±0.07)mg/kg,粮食硒(0.049±0.016)mg/kg,粮食T-2毒素(3.82±4.38)μg/kg。结论陕西省儿童大骨节病病情处于基本控制后的平稳低发态势,病区内外环境硒水平的明显升高、饮食结构的明显改善、粮食卫生学质量的提高及经济收入的增加是病情得到控制的主要因素,应进一步深化防治措施落实和加强病区群众健康教育。Objective To further understand the tendency of Kaschin-Beck disease （KBD） and the influence of associated factors on KBD state to provide data for KBD control. Methods 6 national investigating spots and 20 provincial survey spots were selected in KBD prevalence areas. 2568 of 7 ~ 12 year-old children were clinically examined and their right hands were radiologically checked. 600 stable food samples and 300 hair samples were collected to detect the contents of selenium. T-2 toxin were also detected in 180 staple food samples. The relation of other associated factors with case prevalence were investigated. Results Radiological detective rate of KBD was 1.29%, selenium contents in hair and staple food samples were（0.37 ± 0.07）mg/kg and（0.049 ± 0.016） mg/kg respectively. T-2 toxin content in food samples was （3.82 ± 4.38）μg/kg. Conclusions Child KBD in Shaanxi Province is under control in a stable state. Selenium level increasing in environment, improving food structure and nutrition, increasing economic income are main measure of KBD control. Control measure and health education should be further strengthened.

关 键 词：大骨节病 硒 T-2毒素 调查 陕西 病情现状 

分 类 号：R684.1[医药卫生—骨科学]