补体系统在抗钩端螺旋体感染中的作用  

Study on the Effect of Complement System on Preventing Leptospires Infection

作　　者：吴俊英[1] 陈艺林[1] 祖莹[1] 蒋惠荷[1] 李英欣[1] 

机构地区：[1]蚌埠医学院临床微生物免疫学教研室,蚌埠233003

出　　处：《中国人兽共患病杂志》1997年第3期24-26,共3页Chinese Journal of Zoonoses

摘　　要：本文报告感染构端螺旋体的豚鼠及正常豚鼠血清补体50％溶血（CH50）及血清对中性粒细胞（PMN）的趋化作用。结果显示感染组CH50明显降低，血清对PMN的趋化能力明显提高（P＜0．01）；经青霉素治疗后补体活性无明显改变（P＞0．05）。提示补体系统参与了抗钧端螺旋体的感染，并对变态反应的免疫病理损伤有一定作用。The serum 50% complement fixation hemolysis(CH50) and the ploymophonuclear(PMN) chemotactie effect were determined in guinea-pig with leptospires infection and in the control.The results showed that the CH50 were decresed,and the PMN chemotactic effect were higher than that of the contrl(P＜0.001). The results suggested that complement system might play role in preventing leptospires infection and immunologic injury.

关 键 词：钩端螺旋体 补体 

分 类 号：R514.403[医药卫生—内科学]