乳安合剂的制备与质量标准研究  

Preparation and Quality Criteria of Ru'an Mixture

作　　者：谭建伟[1] 杨天才[1] 马秀芬[1] 张福琴[1] 杨威虎[1] 

机构地区：[1]甘肃省妇幼保健院,兰州市730050

出　　处：《中国药房》2007年第33期2588-2590,共3页China Pharmacy

摘　　要：目的:制备乳安合剂,并建立其质量标准。方法:以柴胡、桂枝、当归等药材制成乳安合剂;采用薄层色谱(TLC)法鉴别柴胡、白芍、当归,采用高效液相色谱法测定丹参素的含量。结果:柴胡、白芍、当归的TLC斑点清晰;丹参素的进样量在0.203～2.030μg范围内与峰面积积分值呈良好线性关系(r=0.9998)。结论:乳安合剂处方配伍及制备工艺合理,所建质量标准可用于制剂的质量控制。OBJECTIVE： To preparation Ru＇ an mixture, and establish its quality standard and observe its therapeutic ef- ficacy. METHODS： Ru＇ an mixture was prepared with Radix Bupleuri and Ramulus Cinnamomi and Radix Angelicae Sinensis as raw material. Radix Bupleuri, Radix Paeoniae Alba, and Radix Angelicae Sinensis were identified by TLC and the content of Tanshinol was determined by HPLC.RESULTS： The TLC spots of Radix Bupleuri, Radix Paeoniae Alba, and Radix An- gelicae Sincnsis were all clear. The linear range of Tanshinol was 0. 203-2. 030μg （r = 0.999 8）. The total effect rate in Ru＇ CONCLUSION： Ru＇an mixture is reasonable in preparation technique, controllable in quality.

关 键 词：乳安合剂 制备 质量标准 乳腺增生 

分 类 号：R944.17[医药卫生—药剂学] R283[医药卫生—药学]