甲状腺疾病粗针穿刺活检病理与临床诊断对比  

Bioptic Histopathology in Diagnosing Thyroid Diseases

作　　者：王坚[1] 张泰和[2] 周晓军[2] 王竹兰[1] 冯根宝[1] 黄高升[3] 吴国梁[1] 王燕燕[1] 张克勤[1] 

机构地区：[1]南京军区南京总医院内分泌科,210002 [2]南京军区南京总医院病理科,210002 [3]第四军医大学病理教研室,210002

出　　处：《天津医药》1997年第6期323-325,共3页Tianjin Medical Journal

摘　　要：总结54例甲状腺粗针穿刺活检病例,分析其病理、超微病理改变与临床诊断和实验检查的联系。结果表明,活检成功率为92.6％,病理确诊率为90.7％,活检前临床诊断与病理符合率仅为67.3％。三分之一左右临床诊断为Graves甲亢的患者实为甲亢伴甲状腺炎或桥本甲亢。超微病理检查对自身免疫性甲状腺疾病的鉴别诊断有较大价值。20％以上的桥本甲状腺炎和桥本甲亢患者自身抗体TgAb、TMAb测定结果呈阴性。Fifty-four patients with different kinds of thyroid diseases received coarse needle biopsy (CNB). Histopathologic diagnosis was compared with accuracy of clinical diagnosis and laboratory evaluation. The value of ultrastructural pathology in differentiating autoimmune thyroid diseases (AITD) was also studied in some cases. Of 54 CNB cases ,49 samples(90. 7%) were adequate for histologic diagnosis. The accuracy of prebioptic diagnosis was only 67. 3% contrasted to histopathology. Some patients with thyrotoxic symptoms were histologically Hashitoxicosis(HSHT) or thyrotoxicosis with thyroidi-tis(TTOT). In some patients with histologically diagnosed Hashimoto's thyroiditis(HT) ,the circulat- ing autoantibodies TgAb and TMAb were negative. The ultrastructural pathology was quite helpful in evaluating AITD.

关 键 词：甲状腺 诊断 自身免疫性 甲状腺疾病 活组织检查 

分 类 号：R581.04[医药卫生—内分泌]