前列腺中央腺体MR波谱谱线的信噪比研究  

Signal-noise ratio of MR spectroscopy in the central gland of prostate

作　　者：佟艳军[1] 王霄英[2] 李飞宇[2] 蒋学祥[2] 

机构地区：[1]北京大学航天临床医学院影像科,100039 [2]北京大学第一医院医学影像科,100034

出　　处：《中华放射学杂志》2007年第11期1213-1216,共4页Chinese Journal of Radiology

摘　　要：目的了解前列腺中央腺体 MR 波谱(MRS)谱线的信噪比(sNR)与病变性质的关系。方法对18例因良性前列腺增生(BPH)行经尿道前列腺切除(TURP)术患者的 MRS 谱线作回顾性分析。根据病理结果分为3组:中央腺体偶发癌(IDPC)组5例、腺体增生为主的 BPH(glandularBPH,GBPH)组7例和基质增生为主的 BPH(stromal BPH,SBPH)组6例。统计中央腺体感兴趣区内所有SNR≥5、SNR<5和有脂峰干扰的体素数量及所占比率情况,分析 SNR 与病变性质的关系。结果 18例患者共测量体素3632个,SNR≥5体素1579个(占总测量体素的43%),SNR<5的体素1873个。SBPH 组 SNR<5的体素所占比率(67.6±21.8)%大于 GBPH 组(37.1±14.5)%和 IDPC组(39.9±18.8)%,差异有统计学意义(P<0.05);GBPH 组和 IDPC 组比较,差异无统计学意义(P>0.05)。结论前列腺中央腺体的 MRS 谱线中,部分谱线由于 SNR 低,不能用于代谢物半定量分析,尤以 SBPH 患者的 SNR<5体素所占比率最大。Objective To analyze the signal to noise ratio （SNR） of the MRS of the prostate central gland, and study its relationship with the pathology of the lesions. Methods Eighteen patients who underwent transurethral resection of prostate （TURP） for benign prostate hyperplasia （BPH） were enrolled in this study. They were divided into three groups according to the pathological findings： 7 cases of glandular-BPH （GBPH）, 7 cases of stromal-BPH （SBPH） and 5 cases of incidentally detected prostate carcinoma （IDPC）. The voxels in the central glands with SNR ≥ 5 and SNR 〈 5 were counted, and the relationship between the percentage of voxel with SNR 〈 5 and pathology was analyzed. Results In the 18 cases, the total number of voxels measured in the regions of interest was 3632, and the voxels with SNR≥5 and SNR 〈 5 were 1579 （the percentage is 43% ） and 1873, respectively. The percentage of voxels with SNR 〈5 in SBPH group （67. 6 ± 21.8） % was statistically higher than that in GBPH （37.1 ± 14. 5） % and IDPC （39. 9 ± 18. 8） %. The difference between the group of GBPH and IDPC was not statistically significant. Conclusion More than half of the voxels in the central gland could not be reliably analyzed in the prostate MRS examination because of its low SNR, especially in the case of SBPH.

关 键 词：良性前列腺增生 前列腺癌 磁共振波谱学 

分 类 号：R445.2[医药卫生—影像医学与核医学]