立体定位核芯针活检在乳腺疾病诊断中的应用研究  

Application of stereotactic core needle biopsy in diagnosis of breast disease

作　　者：黄强[1] 葛玲玉[1] 许顺良[1] 林冰影[1] 刘小蕉[2] 

机构地区：[1]浙江大学医学院附属第一医院放射科,杭州310003 [2]浙江大学医学院附属第一医院乳腺外科,杭州310003

出　　处：《中华放射学杂志》2007年第11期1237-1240,共4页Chinese Journal of Radiology

基　　金：浙江省卫生厅科研基金(2003A040)

摘　　要：目的探讨乳腺微小病变行立体定位核芯针活检(SCNB)的临床应用价值。方法采用计算机辅助乳腺三维立体定位系统、弹射式活检枪和16 G 核芯针,对47例乳腺 X 线发现的可疑恶性病变直接行穿刺活检,记录每例的临床和 X 线表现(钙化、结节、结构紊乱等)、穿刺活检诊断、外科术后病理诊断或随访观察资料。比较 SCNB 与外科手术二者的病理诊断结果,统计其诊断符合率。对照分析 SCNB 准确性与病灶 X 线表现的关系,分析 SCNB 成败、误诊原因。结果欲行 SCNB 47例,成功完成44例,未能完成3例。31例患者随后行外科手术,SCNB 诊断与术后病理符合27例,4例SCNB 与术后病理不符。结论 SCNB 具有准确、快速、微创等优势,可减少手术活检数量,及早确诊乳腺疾病,具有良好的临床应用前景。Objective To evaluate the value of stereotactic core needle biopsy（SCNB） in diagnosis of breast lesions. Methods Forty-seven cases were punctured with computer-assisted stereotactic system, spring-loaded biopsy guns and 16 G core needles. The record of each item was collected, including clinical manifestations, descriptions of the mammographic characteristics （such as calcification, mass and architectural distortion）, the pathology of the SCNB and the surgical pathology or mammographic follow-up data. Then the results of SCNB were analyzed based on the comparison of SCNB pathology and the surgical pathology. The reason that SCNB failed and misdioaguosed was inferred from the relationship of SCNB accuracy and the X-ray characteristics. Results Forty-four cases were punctured successfully, 3 cases failed. Thirty-one patients were operated soon after biopsy. The results of 27 SCNB cases agreed well with the final pathology but the other 4 did not. Condusions SCNB as an accurate, time-saving and costeffective method, is also minimally invasive and hardly changes the architecture of the breast. SCNB can diagnose breast lesions in advance, reduces the number of surgical biopsy, and is promising in clinical application.

关 键 词：乳腺疾病 诊断 立体定位技术 活组织检查 针吸 

分 类 号：R446.8[医药卫生—诊断学]