慢性湿疹患者血清胃泌素 抗幽门螺杆菌抗体的检测  

Detection of Gastrin and Helicobacter Pylori Antibody in Sera of Chronic Eczema

作　　者：王香兰[1] 李张军[1] 许庆强[1] 任建文[1] 周鹏军[1] 

机构地区：[1]西安交通大学第二附属医院皮肤科,陕西西安710004

出　　处：《中国皮肤性病学杂志》2007年第11期670-671,共2页The Chinese Journal of Dermatovenereology

摘　　要：目的探讨胃泌素和抗幽门螺杆菌(Hp)抗体在慢性湿疹发病中的作用。方法采用放射免疫分析法、金标免疫斑点法分别测定129例慢性湿疹患者血清胃泌素、抗Hp抗体,56例年龄、性别相匹配的健康志愿者作为正常对照。结果慢性湿疹组和正常对照组血清胃泌素水平分别为(145.70±45.92)ng/L,(63.58±21.72)ng/L;两组血清抗Hp抗体阳性率分别为85.27%,51.79%,差异均有显著性(P<0.01)。结论慢性湿疹的发病可能与Hp感染有关。Objective To investigate serum gastrin and Helicobacter pylori Antibody（Hp-Ab） in patients with chronic ec- zema. Methods To detect serum gastrin by radioimmunoassay and to detect serum Hp-Ab by dot-immunogold method, 129 pa- tients with chronic eczema and 56 controls. Results Serum gastrin levels in patients with chronic eczema （ 145.70 ± 45.92 ng/L） and those in controls （63.58 ± 21.72 ng/L）, positive rate of serum Hp-Ab in patients with chronic eczema （85.27%） and that in controls （51.79%）. Conclusion Serum gastrin levels and positive rate of serum Hp-Ab were both significantly higher than those in controls.

关 键 词：慢性湿疹 胃泌素 抗幽门螺杆菌抗体 

分 类 号：R758.23[医药卫生—皮肤病学与性病学]