Experimental and computational studies on the flow fields in aortic aneurysms associated with deployment of AAA stent-grafts  

作　　者：Xiwen Zhang Zhaohui Yao Yan Zhang Shangdong Xu 

机构地区：[1]Department of Engineering Mechanics, Tsinghua University, Beijing 100084, China [2]Institute of Heart, Pulmonary and Vascular Diseases, Capital University of Medical Science Affiliated Beijing Anzhen Hospital, Beijing 100029, China

出　　处：《Acta Mechanica Sinica》2007年第5期495-501,共7页力学学报（英文版）

基　　金：The project was supported by the National Natural Science Foundation of China(10672090)

摘　　要：Pulsatile flow fields in rigid abdominal aortic aneurysm （AAA） models were investigated numerically, and the simulation results are found in good agreement with particle image velocimetry （PIV） measurements. There are one or more vortexes in the AAA bulge, and a fairly high wall shear stress exists at the distal end, and thus the AAA is in danger of rupture. Medical treatment consists of inserting a vascular stent-graft in the AAA, which would decrease the blood impact to the inner walls and reduce wall shear stress so that the rupture could be prevented. A new computational model, based on porous medium model, was developed and results are documented. Therapeutic effect of the stent-graft was verified numerically with the new model.Pulsatile flow fields in rigid abdominal aortic aneurysm （AAA） models were investigated numerically, and the simulation results are found in good agreement with particle image velocimetry （PIV） measurements. There are one or more vortexes in the AAA bulge, and a fairly high wall shear stress exists at the distal end, and thus the AAA is in danger of rupture. Medical treatment consists of inserting a vascular stent-graft in the AAA, which would decrease the blood impact to the inner walls and reduce wall shear stress so that the rupture could be prevented. A new computational model, based on porous medium model, was developed and results are documented. Therapeutic effect of the stent-graft was verified numerically with the new model.

关 键 词：Abdominal aortic aneurysm Numerical simulation Particle image velocimetry Wall shear stress STENT-GRAFT 

分 类 号：Q66[生物学—生物物理学]