净厚朴与姜厚朴水煎液主要药理学比较  

Comparison between Houpo and ginger Houpo in main pharmacology

作　　者：许腊英[1] 胡静[1] 翁德会[1] 李霞[1] 李凯[1] 万芳[1] 

机构地区：[1]湖北中医学院,湖北武汉430061

出　　处：《中国医院药学杂志》2007年第11期1503-1505,共3页Chinese Journal of Hospital Pharmacy

基　　金：湖北省科学技术委员会攻关项目[编号:2002AA304A04]

摘　　要：目的:观察净厚朴和姜厚朴的主要药理学变化。方法:小鼠灌胃数天后,利用经典的小肠推进、盐酸性溃疡、番泻叶致泻、二甲苯耳肿胀实验来比较炮制前后厚朴的双向调节胃肠活动和抗炎作用的变化。结果:以上4项作用,小肠推进作用净厚朴>姜厚朴,抗盐酸性溃疡作用净厚朴<姜厚朴,抗番泻叶腹泻和抗炎作用二者无明显差异。结论:中药厚朴的炮制是有必要的。本实验简单易行,易出结果。OBJECTIVE To observe the main pharmacologic variety of Houpo and ginger Houpo. METHODS After few days of infuseing the drugs to rats, the classic experiments, such as intestinal propulsion, ulceration caused by hydroc-hloric acid,diarrhoea caused by Fanxieye, ear swelling resulted by the xylene were used, then compared the variety of functions. RESULTS The function of intesties propulsion is stronger in Houpo Houpo group than that in ginger Houpo group ,the function of against ulceration caused by hydrochloric acid is stronger in ginger Houpo group,and there is no obvious difference between the groups in the functions of agaist diarrhoea and inflammation. CONCLUSION Magnolia officinalis paozhi integrant.

关 键 词：厚朴 制剂 药理 

分 类 号：R285.6[医药卫生—中药学]